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Phf5a Gene Detail
Summary
  • Symbol
    Phf5a
  • Name
    PHD finger protein 5A
  • Synonyms
    1110007B08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2156864
    NCBI Gene: 68479
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:81748717-81756093 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 38.26 cM, cytoband E
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    244 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2156864
 protein coding gene Chr15:81748717-81756112 (-)
129S1/SvImJ ENSMUSG00200051578
 protein coding gene Chr15:78855719-78863110 (-)
A/J ENSMUSG00195042616
 protein coding gene Chr15:78792674-78800088 (-)
AKR/J ENSMUSG00220051987
 protein coding gene Chr15:78835813-78843227 (-)
BALB/cJ ENSMUSG00180049211
 protein coding gene Chr15:78669632-78677046 (-)
C3H/HeJ ENSMUSG00175042529
 protein coding gene Chr15:78980621-78988035 (-)
C57BL/6NJ ENSMUSG00215052300
 protein coding gene Chr15:78765848-78773240 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020061
 protein coding gene Chr15:75876844-75883575 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210045956
 protein coding gene Chr15:78755706-78763120 (-)
DBA/2J ENSMUSG00185042646
 protein coding gene Chr15:78778917-78786331 (-)
FVB/NJ ENSMUSG00205022897
 protein coding gene Chr15:78501556-78508945 (-)
JF1/MsJ ENSUMUG00000040827
 protein coding gene Chr15:78358350-78365796 (-)
LP/J ENSMUSG00230050891
 protein coding gene Chr15:82103096-82110487 (-)
NOD/ShiLtJ ENSMUSG00190045510
 protein coding gene Chr15:78772804-78780218 (-)
NZO/HlLtJ ENSMUSG00225047552
 protein coding gene Chr15:82439994-82447408 (-)
PWK/PhJ ENSLUMG00010045916
 protein coding gene Chr15:78569960-78577406 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005040821
 protein coding gene Chr15:78848140-78855556 (-)



Homology
more
  • Human Ortholog
    PHF5A, PHD finger protein 5A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHF5A, PHD finger protein 5A
  • Synonyms
    bK223H9.2, INI, Rds3, SAP14b, SF3b14b, SF3B7
  • Links
    NCBI Gene ID: 84844
    UniProt: Q7RTV0

  • Chr Location
    22q13.2; chr22:41459705-41468711 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption may exhibit embryonic lethality at E6. Mice with loss of expression in B cells show defective early B cell development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    55
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    675
  • Tissues
    42
  • cDNA Data
    85
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68479 NCBI Gene Model | MGI Sequence Detail 7377 C57BL/6J ±  kb
    transcript NM_026737 RefSeq | MGI Sequence Detail 1648 C57BL/6  
    polypeptide P83870 UniProt | EBI | MGI Sequence Detail 110 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 86
      Genomic 1
      cDNA 85

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1915729
    References
    more
    • Summaries
      All 63
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 10
      Phenotypes 32
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory