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Eri3 Gene Detail
Summary
  • Symbol
    Eri3
  • Name
    exoribonuclease 3
  • Synonyms
    PINT1, Prnpip1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153887
    NCBI Gene: 140546
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:117407562-117531494 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.46 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2111 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153887
protein coding gene Chr4:117407416-117531494 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028651
protein coding gene Chr4:118544508-118673123 (+)
A/J MGP_AJ_G0028612
protein coding gene Chr4:113973216-114098558 (+)
AKR/J MGP_AKRJ_G0028562
protein coding gene Chr4:116469861-116594589 (+)
BALB/cJ MGP_BALBcJ_G0028633
protein coding gene Chr4:114595290-114720692 (+)
C3H/HeJ MGP_C3HHeJ_G0028347
protein coding gene Chr4:118049017-118174587 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029074
protein coding gene Chr4:123104776-123234750 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026358
protein coding gene Chr4:107999766-108124097 (+)
CAST/EiJ MGP_CASTEiJ_G0027781
protein coding gene Chr4:115255338-115383324 (+)
CBA/J MGP_CBAJ_G0028314
protein coding gene Chr4:126480198-126615411 (+)
DBA/2J MGP_DBA2J_G0028462
protein coding gene Chr4:114592500-114717080 (+)
FVB/NJ MGP_FVBNJ_G0028430
protein coding gene Chr4:113106539-113233439 (+)
LP/J MGP_LPJ_G0028564
protein coding gene Chr4:118715311-118843973 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028457
protein coding gene Chr4:131399786-131528304 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029111
protein coding gene Chr4:117603899-117738692 (+)
PWK/PhJ MGP_PWKPhJ_G0027507
protein coding gene Chr4:111406539-111532841 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027330
protein coding gene Chr4:113924160-114048752 (+)
WSB/EiJ MGP_WSBEiJ_G0027860
protein coding gene Chr4:117504817-117629140 (+)



Homology
more
  • Human Ortholog
    ERI3, ERI1 exoribonuclease family member 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERI3, ERI1 exoribonuclease family member 3
  • Synonyms
    PINT1, PRNPIP
  • Links
    NCBI Gene ID: 79033
    neXtProt AC: NX_O43414
    UniProt: O43414

  • Chr Location
    1p34.1; chr1:44221070-44355279 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033423 Ensembl Gene Model | MGI Sequence Detail 123933 C57BL/6J ±  kb
transcript ENSMUST00000037127 Ensembl | MGI Sequence Detail 1719 Not Applicable  
polypeptide ENSMUSP00000042796 Ensembl | MGI Sequence Detail 337 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 109
    cDNA 108
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 18
  • Earliest
    J:72874 Spielhaupter C, et al., PrPC Directly Interacts with Proteins Involved in Signaling Pathways. J Biol Chem. 2001 Nov 30;276(48):44604-12
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory