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Tgm7 Gene Detail
Summary
  • Symbol
    Tgm7
  • Name
    transglutaminase 7
  • Synonyms
    TGz
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151164
    NCBI Gene: 640543
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120924046-120946877 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.37 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151164
protein coding gene Chr2:120923979-120946877 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026380
protein coding gene Chr2:123976713-123992612 (-)
A/J MGP_AJ_G0026341
protein coding gene Chr2:118902862-118918896 (-)
AKR/J MGP_AKRJ_G0026320
protein coding gene Chr2:122245544-122261510 (-)
BALB/cJ MGP_BALBcJ_G0026354
protein coding gene Chr2:119137959-119154328 (-)
C3H/HeJ MGP_C3HHeJ_G0026100
protein coding gene Chr2:122724337-122740352 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026801
protein coding gene Chr2:128040175-128056400 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024181
protein coding gene Chr2:113945774-113961644 (-)
CAST/EiJ MGP_CASTEiJ_G0025562
protein coding gene Chr2:123044202-123060035 (-)
CBA/J MGP_CBAJ_G0026076
protein coding gene Chr2:132503694-132519597 (-)
DBA/2J MGP_DBA2J_G0026215
protein coding gene Chr2:118304183-118319930 (-)
FVB/NJ MGP_FVBNJ_G0026177
protein coding gene Chr2:117122592-117138558 (-)
LP/J MGP_LPJ_G0026316
protein coding gene Chr2:124235223-124251019 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026196
protein coding gene Chr2:136800604-136816619 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026856
protein coding gene Chr2:122359117-122375132 (-)
PWK/PhJ MGP_PWKPhJ_G0025298
protein coding gene Chr2:117905017-117922057 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025097
protein coding gene Chr2:121576236-121592141 (-)
WSB/EiJ MGP_WSBEiJ_G0025631
protein coding gene Chr2:123188284-123204241 (-)



Homology
more
  • Human Ortholog
    TGM7, transglutaminase 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TGM7, transglutaminase 7
  • Synonyms
    TGMZ
  • Links
    NCBI Gene ID: 116179
    neXtProt AC: NX_Q96PF1
    UniProt: Q96PF1

  • Chr Location
    15q15.2-q15.3; chr15:43276271-43302255 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079103 Ensembl Gene Model | MGI Sequence Detail 22832 C57BL/6J ±  kb
transcript ENSMUST00000110675 Ensembl | MGI Sequence Detail 2157 Not Applicable  
polypeptide ENSMUSP00000106303 Ensembl | MGI Sequence Detail 710 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR014756 Immunoglobulin E-set
    IPR013783 Immunoglobulin-like fold
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR023608 Protein-glutamine gamma-glutamyltransferase, animal
    IPR013808 Transglutaminase, active site
    IPR008958 Transglutaminase, C-terminal
    IPR036238 Transglutaminase, C-terminal domain superfamily
    IPR002931 Transglutaminase-like
    IPR036985 Transglutaminase-like superfamily
    IPR001102 Transglutaminase, N-terminal
Molecular
Reagents
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  • All nucleic 2
    cDNA 1
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory