About   Help   FAQ
Il22b Gene Detail
Summary
  • Symbol
    Il22b
  • Name
    interleukin 22B
  • Synonyms
    Iltifb, IL-TIFb
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151139
    NCBI Gene: 116849
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr10:118125534-118130943 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 66.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151139
 protein coding gene Chr10:118125534-118130943 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0017741
 protein coding gene Chr10:116445728-116450838 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0017705
 protein coding gene Chr10:116833170-116838280 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0018160
 protein coding gene Chr10:125360602-125364353 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015841
 protein coding gene Chr10:110981874-110987000 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0017604
 protein coding gene Chr10:115578604-115585626 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0017678
 protein coding gene Chr10:121834072-121837605 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017628
 protein coding gene Chr10:133140820-133145894 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018201
 protein coding gene Chr10:120022682-120028372 (-)
PWK/PhJ MGP_PWKPhJ_G0016874
 protein coding gene Chr10:115686885-115691984 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016665
 protein coding gene Chr10:118837305-118840846 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IL22, interleukin 22
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IL22, interleukin 22
  • Synonyms
    IL-21, IL-22, IL-D110, ILTIF, IL-TIF, TIFa, TIFIL-23, zcyto18
  • Links
    NCBI Gene ID: 50616
    neXtProt AC: NX_Q9GZX6
    UniProt: Q9GZX6

  • Chr Location
    12q15; chr12:68248242-68253604 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 116849 NCBI Gene Model | MGI Sequence Detail 5410 C57BL/6J ±  kb
transcript NM_054079 RefSeq | MGI Sequence Detail 1111 C57BL/6  
polypeptide Q9JJY8 UniProt | EBI | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory