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Cnnm3 Gene Detail
Summary
  • Symbol
    Cnnm3
  • Name
    cyclin M3
  • Synonyms
    Acdp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151055
    NCBI Gene: 94218
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36550948-36567318 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 15.30 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    59 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151055
 protein coding gene Chr1:36550948-36567318 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015925
 protein coding gene Chr1:35043717-35060068 (+)
A/J MGP_AJ_G0015909
 protein coding gene Chr1:34110198-34126552 (+)
AKR/J MGP_AKRJ_G0015864
 protein coding gene Chr1:34592568-34608942 (+)
BALB/cJ MGP_BALBcJ_G0015863
 protein coding gene Chr1:33798895-33815203 (+)
C3H/HeJ MGP_C3HHeJ_G0015696
 protein coding gene Chr1:34781822-34799107 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016316
 protein coding gene Chr1:36636558-36652891 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014038
 protein coding gene Chr1:31163379-31179472 (+)
CAST/EiJ MGP_CASTEiJ_G0015277
 protein coding gene Chr1:34674065-34690399 (+)
CBA/J MGP_CBAJ_G0015668
 protein coding gene Chr1:37585660-37604099 (+)
DBA/2J MGP_DBA2J_G0015769
 protein coding gene Chr1:33445434-33461958 (+)
FVB/NJ MGP_FVBNJ_G0015771
 protein coding gene Chr1:32964129-32981264 (+)
LP/J MGP_LPJ_G0015839
 protein coding gene Chr1:35412337-35428710 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015791
 protein coding gene Chr1:39813919-39831441 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016363
 protein coding gene Chr1:34623469-34639873 (+)
PWK/PhJ MGP_PWKPhJ_G0015060
 protein coding gene Chr1:33194807-33212963 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014842
 protein coding gene Chr1:34573794-34591527 (+)
WSB/EiJ MGP_WSBEiJ_G0015339
 protein coding gene Chr1:34574990-34592653 (+)



Homology
more
  • Human Ortholog
    CNNM3, cyclin and CBS domain divalent metal cation transport mediator 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNNM3, cyclin and CBS domain divalent metal cation transport mediator 3
  • Synonyms
    ACDP3
  • Links
    NCBI Gene ID: 26505
    neXtProt AC: NX_Q8NE01
    UniProt: Q8NE01

  • Chr Location
    2q11.2; chr2:96816245-96837466 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    51
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94218 NCBI Gene Model | MGI Sequence Detail 16371 C57BL/6J ±  kb
transcript NM_001039551 RefSeq | MGI Sequence Detail 5292 ZRU/MplStud  
polypeptide Q32NY4 UniProt | EBI | MGI Sequence Detail 713 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    Genomic 2
    cDNA 51

    Microarray probesets 7
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:218619 Hardy S, et al., The protein tyrosine phosphatase PRL-2 interacts with the magnesium transporter CNNM3 to promote oncogenesis. Oncogene. 2015 Feb 19;34(8):986-95
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory