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Semp2l2b Gene Detail
Summary
  • Symbol
    Semp2l2b
  • Name
    SUMO/sentrin specific peptidase 2-like 2B
  • Synonyms
    4930444G20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149738
    NCBI Gene: 114671
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:21942208-21943978 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 9.83 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149738
protein coding gene Chr10:21942206-21943978 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0022684
protein coding gene Chr16:28006424-28008278 (-)
AKR/J MGP_AKRJ_G0022657
protein coding gene Chr16:29049935-29051769 (-)
BALB/cJ MGP_BALBcJ_G0035938
protein coding gene ChrX:97381794-97382808 (-)
C3H/HeJ MGP_C3HHeJ_G0016826
protein coding gene Chr10:19826152-19827756 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031755
protein coding gene Chr6:135237427-135239153 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014012
protein coding gene Chr1:27768326-27773551 (+)
CAST/EiJ MGP_CASTEiJ_G0015252
protein coding gene Chr1:30542136-30545477 (-)
CBA/J MGP_CBAJ_G0016797
protein coding gene Chr10:21342900-21344006 (-)
DBA/2J MGP_DBA2J_G0016905
protein coding gene Chr10:19006986-19008160 (-)
FVB/NJ MGP_FVBNJ_G0029295
protein coding gene Chr5:39672986-39675480 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0033193
protein coding gene Chr8:12313694-12315578 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0021750
protein coding gene Chr16:29748539-29750495 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014816
protein coding gene Chr1:30419014-30420692 (-)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 114671 NCBI Gene Model | MGI Sequence Detail 1771 C57BL/6J ±  kb
transcript NM_053264 RefSeq | MGI Sequence Detail 1771 C57BL/6  
polypeptide NP_444494 RefSeq | MGI Sequence Detail 495 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR003653 Ulp1 protease family, C-terminal catalytic domain
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
References
more
  • Summaries
    All 18
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:74548 Benson KF, et al., Molecular Characterization of the Mouse In(10)17Rk Inversion and Identification of a Novel Muscle-Specific Gene at the Proximal Breakpoint. Genetics. 2002 Jan;160(1):279-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory