Rpl31 MGI Mouse Gene Detail - MGI:2149632

Symbol

Rpl31
Name

ribosomal protein L31
Synonyms

Dts

Feature Type

protein coding gene
IDs

MGI:2149632
NCBI Gene: 114641
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr1:39406932-39410992 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 18.30 cM
Mapping Data

2 experiments

SNPs within 2kb

54 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2149632	protein coding gene	Chr1:39406923-39410992 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0015956	protein coding gene	Chr1:38102325-38106402 (+)
A/J	MGP_AJ_G0015940	protein coding gene	Chr1:37034583-37038060 (+)
AKR/J	MGP_AKRJ_G0015895	protein coding gene	Chr1:37543819-37548198 (+)
BALB/cJ	MGP_BALBcJ_G0015894	protein coding gene	Chr1:36685929-36689417 (+)
C3H/HeJ	MGP_C3HHeJ_G0015727	protein coding gene	Chr1:37788218-37791695 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016347	protein coding gene	Chr1:39692583-39696071 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014069	protein coding gene	Chr1:33997346-34001573 (+)
CAST/EiJ	MGP_CASTEiJ_G0015308	protein coding gene	Chr1:37675087-37679119 (+)
CBA/J	MGP_CBAJ_G0015699	protein coding gene	Chr1:40832953-40836443 (+)
DBA/2J	MGP_DBA2J_G0015800	protein coding gene	Chr1:36324239-36327727 (+)
FVB/NJ	MGP_FVBNJ_G0015802	protein coding gene	Chr1:35860199-35863687 (+)
LP/J	MGP_LPJ_G0015870	protein coding gene	Chr1:38443785-38447274 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015822	protein coding gene	Chr1:42898186-42904086 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016394	protein coding gene	Chr1:37656019-37660073 (+)
PWK/PhJ	MGP_PWKPhJ_G0015091	protein coding gene	Chr1:36134396-36138699 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0014873	protein coding gene	Chr1:37587791-37591910 (+)
WSB/EiJ	MGP_WSBEiJ_G0015370	protein coding gene	Chr1:37599415-37603011 (+)

Human Ortholog

RPL31, ribosomal protein L31

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL31, ribosomal protein L31
Synonyms

L31
Links

HGNC:10334

NCBI Gene ID: 6160

neXtProt AC: NX_P62899

UniProt: P62899
Chr Location

2q11.2; chr2:101002229-101019693 (+) GRCh38.p7

Alliance of Genome Resources

Rpl31 stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPL31
Gene Tree

Rpl31

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Phenotype Summary

4 phenotypes from 2 alleles in 2 genetic backgrounds
1 images
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Chemically induced (other)

1
Gene trapped

2
Spontaneous

2
Genomic Mutations

1 involving Rpl31
Find Mice (IMSR)

12 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Carriers of dominant spontaneous mutations have a shortened, kinked tail with variable expessivity in the tail length and number of kinks.

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All GO Annotations

23
GO References

9

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

718
Tissues

7
cDNA Data

18
Literature Summary

3

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpl31

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Rpl31 interacts with 62 markers (Mir10a, Mir10b, Mir20a, ...) View All

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All Sequences

67
RefSeq

6
UniProt

5
CCDS

CCDS14904.1

Ensembl

ENSMUSG00000073702 (Evidence)
NCBI Gene

114641

			Length	Strain/Species	Flank
genomic	114641	NCBI Gene Model \| MGI Sequence Detail	4061	C57BL/6J	± kb
transcript	NM_001252218	RefSeq \| MGI Sequence Detail	1261	C57BL/6
polypeptide	P62900	UniProt \| EBI \| MGI Sequence Detail	125	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000014214 60S ribosomal protein L31

(term hierarchy)
PDB

6SWA, 7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR000054 Ribosomal protein L31e

IPR020052 Ribosomal protein L31e, conserved site

IPR023621 Ribosomal protein L31e domain superfamily

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All nucleic 21

cDNA 20

Primer pair 1

Microarray probesets 15

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MGI:4456871

Summaries

All 39

Developmental Gene Expression 3

Gene Ontology 9

Phenotypes 6
Earliest

J:60564 Cabibbo A, et al., ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum. J Biol Chem. 2000 Feb 18;275(7):4827-33
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rpl31:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr6375	Chr1:39406897-39406929 (+)	-19 bp
Tssr6376	Chr1:39406955-39406966 (+)	29 bp
Tssr6377	Chr1:39406981-39407012 (+)	65 bp
Tssr6378	Chr1:39407183-39407209 (+)	264 bp
Tssr6379	Chr1:39408265-39408279 (+)	1,340 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Copyright, and Privacy Statement Send questions and comments to User Support.	last database update 03/14/2023 MGI 6.22