Ncr3-ps Pseudogene Detail

Summary

• Symbol
  Ncr3-ps
• Name
  natural cytotoxicity triggering receptor 3, pseudogene
• Synonyms
  1C7, Ly117, Ncr3

• Feature Type
  pseudogene
• IDs
  MGI:2149332
  NCBI Gene: 667612
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr17:35399511-35403638 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 18.59 cM
• Mapping Data
  2 experiments

Strain
Comparison

• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2149332	pseudogene	Chr17:35399511-35403785 (+)
129S1/SvImJ	ENSMUSG00200051430	pseudogene	Chr17:31103631-31107758 (+)
A/J	ENSMUSG00195049006	pseudogene	Chr17:32005825-32009940 (+)
AKR/J	ENSMUSG00220052106	pseudogene	Chr17:31032861-31038364 (+)
BALB/cJ	ENSMUSG00180044794	pseudogene	Chr17:31375680-31379795 (+)
C3H/HeJ	ENSMUSG00175041852	pseudogene	Chr17:30918974-30924481 (+)
C57BL/6NJ	ENSMUSG00215053115	pseudogene	Chr17:30943856-30947984 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0037196	pseudogene	Chr17:31924256-31928602 (+)
CAST/EiJ	ENSTCUG00005051752	pseudogene	Chr17:31961184-31966725 (+)
CBA/J	ENSMUSG00210052760	pseudogene	Chr17:30741079-30746578 (+)
DBA/2J	ENSMUSG00185054703	pseudogene	Chr17:33394913-33399028 (+)
FVB/NJ	ENSMUSG00205053657	pseudogene	Chr17:31261352-31266854 (+)
JF1/MsJ	ENSUMUG00000057382	pseudogene	Chr17:32645828-32651301 (+)
LP/J	ENSMUSG00230054723	pseudogene	Chr17:34501876-34506003 (+)
NOD/ShiLtJ	ENSMUSG00190053812	pseudogene	Chr17:30862444-30866571 (+)
NZO/HlLtJ	ENSMUSG00225055030	pseudogene	Chr17:36514358-36519813 (+)
PWK/PhJ	ENSLUMG00010046992	pseudogene	Chr17:30480589-30484714 (+)
SPRET/EiJ	ENSMSPG00010050751	pseudogene	Chr17:31663442-31668900 (+)
WSB/EiJ	ENSIUOG00005051522	pseudogene	Chr17:31589815-31595334 (+)

Homology

• Human Ortholog
  NCR3, natural cytotoxicity triggering receptor 3

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  NCR3, natural cytotoxicity triggering receptor 3
  
• Synonyms
  1C7, CD337, LY117, MALS, NKp30
• Links
  HGNC:19077

  NCBI Gene ID: 259197

  UniProt: O14931

  
  
• Chr Location
  6p21.33; chr6:31588895-31593217 (-)  GRCh38

---

• MGI Vertebrate Homology
  Ncr3-ps stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: NCR3
• Gene Tree
  Ncr3-ps
  

Human Diseases

• Diseases
  1 with human NCR3 associations

				Human Disease	Mouse Models
				malaria IDs malaria       DOID:12365 DOID:12552 EFO:0001068 ICD10CM:B54 ICD9CM:084 ICD9CM:084.6 MESH:D008288 NCI:C34797 ORDO:673 UMLS_CUI:C0024530

Click on a disease name to see all genes associated with that disease.

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas
• Other Vertebrate Links
  Xenbase ncr3

Sequences &
Gene Models

• All Sequences
  25
• RefSeq
  2

• Ensembl
  ENSMUSG00000086076 (Evidence)
• NCBI Gene
  667612

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000086076	Ensembl Gene Model | MGI Sequence Detail	4128	C57BL/6J
transcript	ENSMUST00000134687	Ensembl | MGI Sequence Detail	525	Not Applicable

Other
Accession IDs

MGI:3644572

References

• Summaries
  All 13
• Earliest
  J:44259 de Baey A, et al., Complex expression pattern of the TNF region gene LST1 through differential regulation, initiation, and alternative splicing. Genomics. 1997 Nov 1;45(3):591-600
• Latest
  J:189856 Zhang T, et al., An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo. J Immunol. 2012 Sep 1;189(5):2290-9