AI661453 Gene Detail

Summary

• Symbol
  AI661453
• Name
  expressed sequence AI661453

• Feature Type
  protein coding gene
• IDs
  MGI:2146908
  NCBI Gene: 224833
• Alliance
  gene page
• Transcription Start Sites
  6 TSS

Location &
Maps

• Sequence Map
  Chr17:47747564-47781563 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 23.18 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  301 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2146908	protein coding gene	Chr17:47747540-47781563 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0023845	protein coding gene	Chr17:48592878-48629040 (+)
A/J	MGP_AJ_G0023805	protein coding gene	Chr17:47378925-47413121 (+)
AKR/J	MGP_AKRJ_G0023774	protein coding gene	Chr17:47763237-47797254 (+)
BALB/cJ	MGP_BALBcJ_G0023807	protein coding gene	Chr17:47294568-47328551 (+)
C3H/HeJ	MGP_C3HHeJ_G0023570	protein coding gene	Chr17:48512811-48546308 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024251	protein coding gene	Chr17:50648652-50682643 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0021700	protein coding gene	Chr17:44137428-44174686 (+)
CAST/EiJ	MGP_CASTEiJ_G0023051	protein coding gene	Chr17:48608917-48647371 (+)
CBA/J	MGP_CBAJ_G0023547	protein coding gene	Chr17:52499489-52532417 (+)
DBA/2J	MGP_DBA2J_G0023675	protein coding gene	Chr17:46137737-46171205 (+)
FVB/NJ	MGP_FVBNJ_G0023641	protein coding gene	Chr17:45783944-45818861 (+)
LP/J	MGP_LPJ_G0023755	protein coding gene	Chr17:49265142-49303008 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0023669	protein coding gene	Chr17:51984440-52022265 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024296	protein coding gene	Chr17:48126719-48162698 (+)
PWK/PhJ	MGP_PWKPhJ_G0022797	protein coding gene	Chr17:45500645-45536202 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0022612	protein coding gene	Chr17:45022700-45057122 (+)
WSB/EiJ	MGP_WSBEiJ_G0023117	protein coding gene	Chr17:48707033-48742594 (+)

Homology

• Human Ortholog
  C6orf132, chromosome 6 open reading frame 132

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  C6orf132, chromosome 6 open reading frame 132
  
• Synonyms
  bA7K24.2
• Links
  HGNC:21288

  NCBI Gene ID: 647024

  neXtProt AC: NX_Q5T0Z8

  UniProt: Q5T0Z8

  
  
• Chr Location
  6p21.1; chr6:42101119-42142977 (-)  GRCh38.p7

---

• Alliance of Genome Resources
  AI661453 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: C6orf132
• Gene Tree
  AI661453
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  3
• Gene trapped
  3
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  17 strains or lines available

Expression

• Assay Results
  708
• Tissues
  2
• cDNA Data
  12
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• AI661453 interacts with 162 markers (Mir10a, Mir10b, Mir18, ...) View All

Sequences &
Gene Models

• All Sequences
  31
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS50131.1

• Ensembl
  ENSMUSG00000034382 (Evidence)
• NCBI Gene
  224833

Representative Sequences			Length	Strain/Species
genomic	224833	NCBI Gene Model | MGI Sequence Detail	34000	C57BL/6J
transcript	NM_145489	RefSeq | MGI Sequence Detail	5032	Not Specified
polypeptide	Q91Z58	UniProt | EBI | MGI Sequence Detail	1206	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000059821 uncharacterized protein C6orf132
  (term hierarchy)

Molecular
Reagents

• All nucleic 13

  cDNA 13

  
  

  Microarray probesets 3

References

• Summaries
  All 23

  Developmental Gene Expression 2

  Phenotypes 3
• Earliest
  J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
• Latest
  J:304253 Jones MR, et al., A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis. Front Genet. 2018;9:746

TSS for AI661453:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr144911	Chr17:47747510-47747520 (+)	-49 bp
Tssr144912	Chr17:47747526-47747533 (+)	-34 bp
Tssr144913	Chr17:47747541-47747564 (+)	-11 bp
Tssr144914	Chr17:47747572-47747583 (+)	14 bp
Tssr144915	Chr17:47747656-47747668 (+)	98 bp
Tssr144916	Chr17:47779262-47779303 (+)	31,719 bp