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Sack1f Gene Detail
Summary
  • Symbol
    Sack1f
  • Name
    scaffolding CK1 anchoring protein F
  • Synonyms
    Fam83f, MGC:27770
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146227
    NCBI Gene: 213956
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:80556048-80584626 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    703 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146227
protein coding gene Chr15:80555829-80584626 (+)
129S1/SvImJ ENSMUSG00200051744
protein coding gene Chr15:77658289-77686870 (+)
A/J ENSMUSG00195051104
protein coding gene Chr15:77604986-77633566 (+)
AKR/J ENSMUSG00220050098
protein coding gene Chr15:77648103-77676680 (+)
BALB/cJ ENSMUSG00180049832
protein coding gene Chr15:77482017-77510595 (+)
C3H/HeJ ENSMUSG00175040340
protein coding gene Chr15:77793080-77821658 (+)
C57BL/6NJ ENSMUSG00215052437
protein coding gene Chr15:77566745-77595323 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020042
protein coding gene Chr15:74694224-74723264 (+)
CAST/EiJ ENSTCUG00005045051
protein coding gene Chr15:77098745-77127368 (+)
CBA/J ENSMUSG00210036264
protein coding gene Chr15:77568226-77596801 (+)
DBA/2J ENSMUSG00185041290
protein coding gene Chr15:77590759-77619344 (+)
FVB/NJ ENSMUSG00205043994
protein coding gene Chr15:77305505-77334083 (+)
JF1/MsJ ENSUMUG00000028727
protein coding gene Chr15:77156274-77184828 (+)
LP/J ENSMUSG00230052158
protein coding gene Chr15:80906658-80935237 (+)
NOD/ShiLtJ ENSMUSG00190047687
protein coding gene Chr15:77585301-77613876 (+)
NZO/HlLtJ ENSMUSG00225049837
protein coding gene Chr15:81244127-81272646 (+)
PWK/PhJ ENSLUMG00010038773
protein coding gene Chr15:77376105-77404704 (+)
SPRET/EiJ ENSMSPG00010048191
protein coding gene Chr15:79038390-79066676 (+)
WSB/EiJ ENSIUOG00005048044
protein coding gene Chr15:77651365-77679951 (+)



Homology
more
  • Human Ortholog
    SACK1F, scaffolding CK1 anchoring protein F
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SACK1F, scaffolding CK1 anchoring protein F
  • Synonyms
    FAM83F
  • Links
    NCBI Gene ID: 113828
    UniProt: Q8NEG4

  • Chr Location
    22q13.1; chr22:39994954-40043534 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022408 Ensembl Gene Model | MGI Sequence Detail 28579 C57BL/6J ±  kb
transcript ENSMUST00000023044 Ensembl | MGI Sequence Detail 2993 Not Applicable  
polypeptide ENSMUSP00000023044 Ensembl | MGI Sequence Detail 495 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 4
Other
Accession IDs
less
MGI:8327526
References
more
  • Summaries
    All 51
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory