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Fam149b Gene Detail
Summary
  • Symbol
    Fam149b
  • Name
    family with sequence similarity 149, member B
  • Synonyms
    MGC:32264, mKIAA0974
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145567
    NCBI Gene: 105428
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:20398230-20433559 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 11.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145567
protein coding gene Chr14:20398221-20433559 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021032
protein coding gene Chr14:13094512-13134845 (+)
A/J MGP_AJ_G0020981
protein coding gene Chr14:12798549-12833947 (+)
AKR/J MGP_AKRJ_G0020958
protein coding gene Chr14:13321715-13358212 (+)
BALB/cJ MGP_BALBcJ_G0020984
protein coding gene Chr14:12907056-12942337 (+)
C3H/HeJ MGP_C3HHeJ_G0020768
protein coding gene Chr14:13257180-13294171 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021417
protein coding gene Chr14:13598553-13633871 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018985
protein coding gene Chr14:13107977-13143035 (+)
CAST/EiJ MGP_CASTEiJ_G0020292
protein coding gene Chr14:13023968-13059069 (+)
CBA/J MGP_CBAJ_G0020734
protein coding gene Chr14:14289533-14324780 (+)
DBA/2J MGP_DBA2J_G0020857
protein coding gene Chr14:12628645-12664074 (+)
FVB/NJ MGP_FVBNJ_G0020840
protein coding gene Chr14:12520470-12559503 (+)
LP/J MGP_LPJ_G0020933
protein coding gene Chr14:13315381-13352314 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020866
protein coding gene Chr14:14065019-14101954 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021450
protein coding gene Chr14:13109503-13145910 (+)
PWK/PhJ MGP_PWKPhJ_G0020041
protein coding gene Chr14:12189416-12225094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019863
protein coding gene Chr14:12883049-12921660 (+)
WSB/EiJ MGP_WSBEiJ_G0020348
protein coding gene Chr14:13093537-13129772 (+)



Homology
more
  • Human Ortholog
    FAM149B1, family with sequence similarity 149 member B1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM149B1, family with sequence similarity 149 member B1
  • Synonyms
    JBTS36, KIAA0974
  • Links
    NCBI Gene ID: 317662
    neXtProt AC: NX_Q96BN6
    UniProt: Q96BN6

  • Chr Location
    10q22.2; chr10:73168119-73244504 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human FAM149B1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039599 Ensembl Gene Model | MGI Sequence Detail 35330 C57BL/6J ±  kb
transcript ENSMUST00000225942 Ensembl | MGI Sequence Detail 2151 Not Applicable  
polypeptide ENSMUSP00000153645 Ensembl | MGI Sequence Detail 606 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145636
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
  • Latest
    J:181631 Gehman LT, et al., The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Genes Dev. 2012 Mar 1;26(5):445-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/19/2023
MGI 6.22
The Jackson Laboratory