Gfod1 MGI Mouse Gene Detail - MGI:2145304 - glucose-fructose oxidoreductase domain containing 1

Gfod1 Gene Detail

Symbol

Gfod1
Name

glucose-fructose oxidoreductase domain containing 1

Feature Type

protein coding gene
IDs

MGI:2145304
NCBI Gene: 328232
Alliance

genome feature page
Transcription Start Sites

9 TSS

Sequence Map

Chr13:43348721-43457648 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 21.41 cM
Mapping Data

1 experiment

SNPs within 2kb

2988 from dbSNP Build 142
Strain Annotations

3

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2145304	protein coding gene	Chr13:43348716-43457648 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	ENSMUSG00215005439	protein coding gene	Chr13:40091325-40200258 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018467	protein coding gene	Chr13:38472105-38570160 (-)
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
JF1/MsJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

GFOD1, Gfo/Idh/MocA-like oxidoreductase domain containing 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

GFOD1, Gfo/Idh/MocA-like oxidoreductase domain containing 1
Synonyms

ADG-90, C6orf114
Links

HGNC:21096

NCBI Gene ID: 54438

UniProt: Q9NXC2
Chr Location

6p24.1-p23; chr6:13357830-13487662 (-) GRCh38

MGI Vertebrate Homology

Gfod1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: GFOD1
Gene Tree

Gfod1

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Phenotype Summary

10 phenotype references

All Mutations and Alleles

14
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

8
Targeted

3
Genomic Mutations

1 involving Gfod1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

26 strains or lines available

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All GO Annotations

5
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

644
Tissues

40
cDNA Data

22
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase gfod1

ZFIN gfod1

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All Sequences

27
RefSeq

4
UniProt

2
CCDS

CCDS26477.1

Ensembl

ENSMUSG00000051335 (Evidence)
NCBI Gene

328232

			Length	Strain/Species	Flank
genomic	ENSMUSG00000051335	Ensembl Gene Model \| MGI Sequence Detail	108928	C57BL/6J	± kb
transcript	ENSMUST00000055341	Ensembl \| MGI Sequence Detail	6928	Not Applicable
polypeptide	ENSMUSP00000062662	Ensembl \| MGI Sequence Detail	390	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000030869 glucose-fructose oxidoreductase domain-containing protein 1

(term hierarchy)
InterPro Domains

IPR050463 Gfo/Idh/MocA family oxidoreductases and glycosidases

IPR055170 GFO/IDH/MocA-like oxidoreductase domain

IPR000683 Gfo/Idh/MocA-like oxidoreductase, N-terminal

IPR036291 NAD(P)-binding domain superfamily

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All nucleic 22

cDNA 22

Microarray probesets 7

Summaries

All 36

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 10
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Gfod1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr122254	Chr13:43457775-43457785 (-)	-132 bp
Tssr122253	Chr13:43457629-43457689 (-)	-11 bp
Tssr122252	Chr13:43457607-43457622 (-)	33 bp
Tssr122251	Chr13:43457594-43457606 (-)	48 bp
Tssr122250	Chr13:43445983-43445989 (-)	11,662 bp
Tssr122249	Chr13:43424768-43424772 (-)	32,878 bp
Tssr122248	Chr13:43422435-43422445 (-)	35,208 bp
Tssr4056	Chr13:43419898-43419910 (-)	37,744 bp
Tssr122246	Chr13:43380383-43380384 (-)	77,264 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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