Tasor2 MGI Mouse Gene Detail - MGI:2145274 - transcription activation suppressor family member 2

Symbol

Tasor2
Name

transcription activation suppressor family member 2
Synonyms

BC016423, Fam208b, MGC:25933

Feature Type

protein coding gene
IDs

MGI:2145274
NCBI Gene: 105203
Alliance

gene page
Transcription Start Sites

11 TSS

Sequence Map

Chr13:3616035-3661108 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 1.99 cM
Mapping Data

2 experiments

SNPs within 2kb

268 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2145274	protein coding gene	Chr13:3615905-3661108 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020194	protein coding gene	Chr13:36876-89052 (-)
A/J	MGP_AJ_G0020150	protein coding gene	Chr13:157393-202202 (-)
AKR/J	MGP_AKRJ_G0020125	protein coding gene	Chr13:139046-186876 (-)
BALB/cJ	MGP_BALBcJ_G0020133	protein coding gene	Chr13:129758-178315 (-)
C3H/HeJ	MGP_C3HHeJ_G0019937	protein coding gene	Chr13:209496-257547 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0020580	protein coding gene	Chr13:108419-158779 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018192	protein coding gene	Chr13:102133-145310 (-)
CAST/EiJ	MGP_CASTEiJ_G0019477	protein coding gene	Chr13:49139-96898 (-)
CBA/J	MGP_CBAJ_G0019904	protein coding gene	Chr13:138528-189878 (-)
DBA/2J	MGP_DBA2J_G0020021	protein coding gene	Chr13:53303-101559 (-)
FVB/NJ	MGP_FVBNJ_G0020006	protein coding gene	Chr13:49059-96630 (-)
LP/J	MGP_LPJ_G0020095	protein coding gene	Chr13:113814-160036 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020042	protein coding gene	Chr13:140955-191053 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020609	protein coding gene	Chr13:121907-174246 (-)
PWK/PhJ	MGP_PWKPhJ_G0019239	protein coding gene	Chr13:115114-160481 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019044	protein coding gene	Chr13:168087-212215 (-)
WSB/EiJ	MGP_WSBEiJ_G0019535	protein coding gene	Chr13:43396-90314 (-)

Human Ortholog

TASOR2, transcription activation suppressor family member 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TASOR2, transcription activation suppressor family member 2
Synonyms

bA318E3.2, C10orf18, FAM208B
Links

HGNC:23484

NCBI Gene ID: 54906

neXtProt AC: NX_Q5VWN6

UniProt: Q5VWN6
Chr Location

10p15.1; chr10:5684731-5763779 (+) GRCh38

Alliance of Genome Resources

Tasor2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TASOR2
Gene Tree

Tasor2

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Endonuclease-mediated

3
Gene trapped

6
Targeted

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

71 strains or lines available

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All GO Annotations

4
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

708
Tissues

2
cDNA Data

14
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tasor2

ZFIN tasor2

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Tasor2 interacts with 205 markers (Mir1a-1, Mir1a-2, Mir1b, ...) View All

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All Sequences

61
RefSeq

10
UniProt

5
CCDS

CCDS49201.1

Ensembl

ENSMUSG00000033799 (Evidence)
NCBI Gene

105203

			Length	Strain/Species	Flank
genomic	ENSMUSG00000033799	Ensembl Gene Model \| MGI Sequence Detail	45074	C57BL/6J	± kb
transcript	ENSMUST00000096069	Ensembl \| MGI Sequence Detail	8338	Not Applicable
polypeptide	ENSMUSP00000093774	Ensembl \| MGI Sequence Detail	2382	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000031017 protein TASOR 2

(term hierarchy)
InterPro Domains

IPR022168 Golgi associated RAB2 interactor protein-like, Rab2B-binding domain

IPR046432 TASOR

IPR022188 TASOR, DUF3715

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All nucleic 14

cDNA 14

Microarray probesets 3

Summaries

All 34

Developmental Gene Expression 1

Gene Ontology 3

Phenotypes 6
Earliest

J:26089 Janoueix-Lerosey I, et al., Two-hybrid system screen with the small GTP-binding protein Rab6. Identification of a novel mouse GDP dissociation inhibitor isoform and two other potential partners of Rab6. J Biol Chem. 1995 Jun 16;270(24):14801-8
Latest

J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

TSS for Tasor2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr121286	Chr13:3661189-3661210 (-)	-92 bp
Tssr121285	Chr13:3661134-3661147 (-)	-33 bp
Tssr121284	Chr13:3661064-3661118 (-)	17 bp
Tssr121283	Chr13:3661036-3661062 (-)	59 bp
Tssr121282	Chr13:3661017-3661034 (-)	82 bp
Tssr121281	Chr13:3661002-3661013 (-)	100 bp
Tssr121280	Chr13:3660982-3660998 (-)	118 bp
Tssr121279	Chr13:3660281-3660300 (-)	817 bp
Tssr121278	Chr13:3660265-3660270 (-)	840 bp
Tssr121277	Chr13:3651482-3651494 (-)	9,620 bp
Tssr121276	Chr13:3651458-3651471 (-)	9,643 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/19/2023 MGI 6.22