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Cog5 Gene Detail
Summary
  • Symbol
    Cog5
  • Name
    component of oligomeric golgi complex 5
  • Synonyms
    5430405C01Rik, GOLTC1, GTC90
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145130
    NCBI Gene: 238123
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:31704868-31987629 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 13.68 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1212 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145130
protein coding gene Chr12:31704848-31987629 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019665
protein coding gene Chr12:29620447-29922046 (+)
A/J MGP_AJ_G0019632
protein coding gene Chr12:28774861-29067186 (+)
AKR/J MGP_AKRJ_G0019603
protein coding gene Chr12:29697127-29990911 (+)
BALB/cJ MGP_BALBcJ_G0019609
protein coding gene Chr12:28999978-29290716 (+)
C3H/HeJ MGP_C3HHeJ_G0019413
protein coding gene Chr12:29566947-29866594 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020056
protein coding gene Chr12:30546605-30851460 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017681
protein coding gene Chr12:28063765-28356619 (+)
CAST/EiJ MGP_CASTEiJ_G0018968
protein coding gene Chr12:24566839-24862540 (+)
CBA/J MGP_CBAJ_G0019385
protein coding gene Chr12:31531891-31844800 (+)
DBA/2J MGP_DBA2J_G0019498
protein coding gene Chr12:28607531-28890056 (+)
FVB/NJ MGP_FVBNJ_G0019489
protein coding gene Chr12:28401412-28685675 (+)
LP/J MGP_LPJ_G0019568
protein coding gene Chr12:29713655-30013811 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019524
protein coding gene Chr12:31168753-31487313 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020096
protein coding gene Chr12:29225698-29521126 (+)
PWK/PhJ MGP_PWKPhJ_G0018735
protein coding gene Chr12:23338947-23632480 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018523
protein coding gene Chr12:23810304-24105668 (+)
WSB/EiJ MGP_WSBEiJ_G0019018
protein coding gene Chr12:29457507-29756727 (+)



Homology
more
  • Human Ortholog
    COG5, component of oligomeric golgi complex 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COG5, component of oligomeric golgi complex 5
  • Synonyms
    CDG2I, GOLTC1, GTC90
  • Links
    NCBI Gene ID: 10466
    neXtProt AC: NX_Q9UP83
    UniProt: Q9UP83

  • Chr Location
    7q22.3; chr7:107201372-107564261 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human COG5 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035933 Ensembl Gene Model | MGI Sequence Detail 282762 C57BL/6J ±  kb
    transcript ENSMUST00000036862 Ensembl | MGI Sequence Detail 2997 Not Applicable  
    polypeptide ENSMUSP00000044797 Ensembl | MGI Sequence Detail 829 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 58
      cDNA 58

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2145129
    References
    more
    • Summaries
      All 35
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/19/2023
    MGI 6.22
    The Jackson Laboratory