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Stac2 Gene Detail
Summary
  • Symbol
    Stac2
  • Name
    SH3 and cysteine rich domain 2
  • Synonyms
    24b2, 24b2/STAC2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144518
    NCBI Gene: 217154
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97927449-97944288 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 61.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144518
 protein coding gene Chr11:97927449-97944288 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019049
 protein coding gene Chr11:100529809-100554514 (-)
A/J MGP_AJ_G0019017
 protein coding gene Chr11:96369268-96386859 (-)
AKR/J MGP_AKRJ_G0018987
 protein coding gene Chr11:99361055-99377793 (-)
BALB/cJ MGP_BALBcJ_G0018990
 protein coding gene Chr11:96868166-96886065 (-)
C3H/HeJ MGP_C3HHeJ_G0018804
 protein coding gene Chr11:99489236-99508016 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019443
 protein coding gene Chr11:103625742-103642970 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017074
 protein coding gene Chr11:93822839-93840127 (-)
CAST/EiJ MGP_CASTEiJ_G0018358
 protein coding gene Chr11:100353799-100374609 (-)
CBA/J MGP_CBAJ_G0018775
 protein coding gene Chr11:107917500-107934233 (-)
DBA/2J MGP_DBA2J_G0018883
 protein coding gene Chr11:95919388-95938312 (-)
FVB/NJ MGP_FVBNJ_G0018872
 protein coding gene Chr11:95422020-95441388 (-)
LP/J MGP_LPJ_G0018953
 protein coding gene Chr11:101021029-101040534 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018899
 protein coding gene Chr11:107733455-107753862 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019483
 protein coding gene Chr11:99681019-99704987 (-)
PWK/PhJ MGP_PWKPhJ_G0018130
 protein coding gene Chr11:96911083-96928943 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017920
 protein coding gene Chr11:99395123-99413404 (-)
WSB/EiJ MGP_WSBEiJ_G0018408
 protein coding gene Chr11:99584355-99605751 (-)



Homology
more
  • Human Ortholog
    STAC2, SH3 and cysteine rich domain 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STAC2, SH3 and cysteine rich domain 2
  • Synonyms
    24b2, 24b2/STAC2
  • Links
    NCBI Gene ID: 342667
    neXtProt AC: NX_Q6ZMT1
    UniProt: Q6ZMT1

  • Chr Location
    17q12; chr17:39210541-39225945 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    758
  • Tissues
    42
  • cDNA Data
    66
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217154 NCBI Gene Model | MGI Sequence Detail 16840 C57BL/6J ±  kb
transcript NM_146028 RefSeq | MGI Sequence Detail 3049 C57BL/6  
polypeptide Q8R1B0 UniProt | EBI | MGI Sequence Detail 408 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:261962 Polster A, et al., Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1. J Gen Physiol. 2018 Apr 2;150(4):613-624
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/19/2023
MGI 6.22 		The Jackson Laboratory