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Tmem17 Gene Detail
Summary
  • Symbol
    Tmem17
  • Name
    transmembrane protein 17
Location &
Maps
more
  • Sequence Map
    Chr11:22462283-22469231 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 14.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    345 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144205
 protein coding gene Chr11:22462088-22469234 (+)
129S1/SvImJ ENSMUSG00200021925
 protein coding gene Chr11:19478260-19485407 (+)
A/J ENSMUSG00195004836
 protein coding gene Chr11:19325665-19332811 (+)
AKR/J ENSMUSG00220003089
 protein coding gene Chr11:19414294-19421439 (+)
BALB/cJ ENSMUSG00180003944
 protein coding gene Chr11:19325445-19332530 (+)
C3H/HeJ ENSMUSG00175007413
 protein coding gene Chr11:19340956-19348102 (+)
C57BL/6NJ ENSMUSG00215003321
 protein coding gene Chr11:19404872-19412019 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016128
 protein coding gene Chr11:18346551-18353927 (+)
CAST/EiJ ENSTCUG00005007088
 protein coding gene Chr11:19303884-19310777 (+)
CBA/J ENSMUSG00210008958
 protein coding gene Chr11:19328547-19335603 (+)
DBA/2J ENSMUSG00185010836
 protein coding gene Chr11:19432479-19439615 (+)
FVB/NJ ENSMUSG00205004401
 protein coding gene Chr11:19385438-19392583 (+)
JF1/MsJ ENSUMUG00000005003
 protein coding gene Chr11:19635445-19642578 (+)
LP/J ENSMUSG00230015284
 protein coding gene Chr11:20475524-20482606 (+)
NOD/ShiLtJ ENSMUSG00190008060
 protein coding gene Chr11:19476144-19483310 (+)
NZO/HlLtJ ENSMUSG00225021647
 protein coding gene Chr11:22510160-22517306 (+)
PWK/PhJ ENSLUMG00010011267
 protein coding gene Chr11:19326494-19333412 (+)
SPRET/EiJ ENSMSPG00010017021
 protein coding gene Chr11:19574479-19581444 (+)
WSB/EiJ ENSIUOG00005009825
 protein coding gene Chr11:19372437-19379594 (+)



Homology
more
  • Human Ortholog
    TMEM17, transmembrane protein 17
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM17, transmembrane protein 17
  • Links
    NCBI Gene ID: 200728
    UniProt: Q86X19

  • Chr Location
    2p15; chr2:62453531-62511894 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    13
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 103765 NCBI Gene Model | MGI Sequence Detail 6949 C57BL/6J ±  kb
    transcript NM_153596 RefSeq | MGI Sequence Detail 1370 C57BL/6  
    polypeptide Q8K0U3 UniProt | EBI | MGI Sequence Detail 198 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144488
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 9
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:178978 Chih B, et al., A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain. Nat Cell Biol. 2011;14(1):61-72
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory