Acad11 MGI Mouse Gene Detail - MGI:2143169 - acyl-Coenzyme A dehydrogenase family, member 11

Symbol

Acad11
Name

acyl-Coenzyme A dehydrogenase family, member 11
Synonyms

5730439E10Rik

Feature Type

protein coding gene
IDs

MGI:2143169
NCBI Gene: 102632
Alliance

genome feature page
Transcription Start Sites

6 TSS

Sequence Map

Chr9:103940923-104004855 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 56.25 cM
Mapping Data

3 experiments

SNPs within 2kb

1894 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2143169	protein coding gene	Chr9:103940576-104004924 (+)
129S1/SvImJ	ENSMUSG00200016537	protein coding gene	Chr9:101101976-101166536 (+)
A/J	ENSMUSG00195018402	protein coding gene	Chr9:100326584-100391160 (+)
AKR/J	ENSMUSG00220038181	protein coding gene	Chr9:100716210-100780772 (+)
BALB/cJ	ENSMUSG00180019887	protein coding gene	Chr9:100643108-100707674 (+)
C3H/HeJ	ENSMUSG00175011734	protein coding gene	Chr9:100985771-101050321 (+)
C57BL/6NJ	ENSMUSG00215011510	protein coding gene	Chr9:100978005-101042356 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032596	protein coding gene	Chr9:99489349-99548131 (+)
CAST/EiJ	ENSTCUG00005012958	protein coding gene	Chr9:100786414-100850892 (+)
CBA/J	ENSMUSG00210015305	protein coding gene	Chr9:100826461-100890656 (+)
DBA/2J	ENSMUSG00185011866	protein coding gene	Chr9:100988054-101052607 (+)
FVB/NJ	ENSMUSG00205016953	protein coding gene	Chr9:100987342-101051880 (+)
JF1/MsJ	ENSUMUG00000031630	protein coding gene	Chr9:100835292-100900011 (+)
LP/J	ENSMUSG00230019991	protein coding gene	Chr9:101137370-101201925 (+)
NOD/ShiLtJ	ENSMUSG00190031217	protein coding gene	Chr9:100628816-100693377 (+)
NZO/HlLtJ	ENSMUSG00225020095	protein coding gene	Chr9:101357526-101422059 (+)
PWK/PhJ	ENSLUMG00010025242	protein coding gene	Chr9:100778257-100842776 (+)
SPRET/EiJ	ENSMSPG00010039344	protein coding gene	Chr9:102644855-102710873 (+)
WSB/EiJ	ENSIUOG00005022009	protein coding gene	Chr9:100055017-100126425 (+)

Human Ortholog

ACAD11, acyl-CoA dehydrogenase family member 11

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ACAD11, acyl-CoA dehydrogenase family member 11
Synonyms

ACAD-11
Links

HGNC:30211

NCBI Gene ID: 84129

UniProt: Q709F0
Chr Location

3q22.1; chr3:132558138-132660104 (-) GRCh38

MGI Vertebrate Homology

Acad11 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ACAD11
Gene Tree

Acad11

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Endonuclease-mediated

4
Gene trapped

3
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

44 strains or lines available

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All GO Annotations

31
GO References

14

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

735
Tissues

122
cDNA Data

13
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase acad11

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All Sequences

62
RefSeq

2
UniProt

4
CCDS

CCDS23458.1

Ensembl

ENSMUSG00000090150 (Evidence)
NCBI Gene

102632

			Length	Strain/Species	Flank
genomic	102632	NCBI Gene Model \| MGI Sequence Detail	63933	C57BL/6J	± kb
transcript	NM_175324	RefSeq \| MGI Sequence Detail	3354	C57BL/6
polypeptide	Q80XL6	UniProt \| EBI \| MGI Sequence Detail	779	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000029259 acyl-CoA dehydrogenase family member 11

(term hierarchy)
PDB

8V3U, 8V3V
EC

1.3.8.8
InterPro Domains

IPR052898 Acyl-CoA dehydrogenase 10-like

IPR041726 Acyl-CoA dehydrogenase family member 10/11, N-terminal

IPR036250 Acyl-CoA dehydrogenase-like, C-terminal

IPR009075 Acyl-CoA dehydrogenase/oxidase, C-terminal

IPR006091 Acyl-CoA dehydrogenase/oxidase, middle domain

IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal

IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily

IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily

IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily

IPR002575 Aminoglycoside phosphotransferase

IPR011009 Protein kinase-like domain superfamily
GlyGen

Q80XL6 1 site, 1 O-linked glycan (1 site)

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All nucleic 14

cDNA 13

Primer pair 1

Microarray probesets 4

Summaries

All 51

Developmental Gene Expression 3

Gene Ontology 14

Phenotypes 12
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:379318 Rashan EH, et al., ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism. Nat Struct Mol Biol. 2025 Sep;32(9):1622-1632

TSS for Acad11:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr86805	Chr9:103940575-103940614 (+)	-328 bp
Tssr86806	Chr9:103940877-103940909 (+)	-30 bp
Tssr86807	Chr9:103940915-103940935 (+)	2 bp
Tssr86808	Chr9:103951263-103951269 (+)	10,343 bp
Tssr86809	Chr9:103953602-103953637 (+)	12,697 bp
Tssr86810	Chr9:103993303-103993304 (+)	52,381 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24