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Gcfc2 Gene Detail
Summary
  • Symbol
    Gcfc2
  • Name
    GC-rich sequence DNA binding factor 2
  • Synonyms
    AW146020
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141656
    NCBI Gene: 330361
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:81900650-81936896 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 35.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    388 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141656
 protein coding gene Chr6:81887543-81936896 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030901
 protein coding gene Chr6:82892406-82928577 (+)
A/J MGP_AJ_G0030870
 protein coding gene Chr6:79701224-79737396 (+)
AKR/J MGP_AKRJ_G0030798
 protein coding gene Chr6:81975360-82011553 (+)
BALB/cJ MGP_BALBcJ_G0030880
 protein coding gene Chr6:79726500-79762687 (+)
C3H/HeJ MGP_C3HHeJ_G0030830
 protein coding gene Chr6:102325873-102362450 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031340
 protein coding gene Chr6:85132644-85168811 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028526
 protein coding gene Chr6:78128685-78167077 (+)
CAST/EiJ MGP_CASTEiJ_G0029989
 protein coding gene Chr6:81986215-82026843 (+)
CBA/J MGP_CBAJ_G0030567
 protein coding gene Chr6:88519163-88557629 (+)
DBA/2J MGP_DBA2J_G0030720
 protein coding gene Chr6:79001744-79037848 (+)
FVB/NJ MGP_FVBNJ_G0030673
 protein coding gene Chr6:78257370-78294053 (+)
LP/J MGP_LPJ_G0030799
 protein coding gene Chr6:82873776-82910862 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030709
 protein coding gene Chr6:92840369-92884794 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031364
 protein coding gene Chr6:81820261-81858937 (+)
PWK/PhJ MGP_PWKPhJ_G0029704
 protein coding gene Chr6:77916973-77953886 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029532
 protein coding gene Chr6:80683248-80722068 (+)
WSB/EiJ MGP_WSBEiJ_G0030070
 protein coding gene Chr6:82252746-82291250 (+)



Homology
more
  • Human Ortholog
    GCFC2, GC-rich sequence DNA-binding factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GCFC2, GC-rich sequence DNA-binding factor 2
  • Synonyms
    C2orf3, DNABF, GCF, TCF9
  • Links
    NCBI Gene ID: 6936
    neXtProt AC: NX_P16383
    UniProt: P16383

  • Chr Location
    2p12; chr2:75652000-75713122 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    9
  • Endonuclease-mediated
    4
  • Gene trapped
    1
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Gcfc2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    40 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035125 Ensembl Gene Model | MGI Sequence Detail 36247 C57BL/6J ±  kb
transcript ENSMUST00000043195 Ensembl | MGI Sequence Detail 4192 Not Applicable  
polypeptide ENSMUSP00000035644 Ensembl | MGI Sequence Detail 769 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 1
    cDNA 8

    Microarray probesets 5
References
more
  • Summaries
    All 34
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:87486 Akeson EC, Chromosomal inversion discovered in C3H/HeJ mice. JAX Notes. 2003;491:15
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory