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Dzank1 Gene Detail
Summary
  • Symbol
    Dzank1
  • Name
    double zinc ribbon and ankyrin repeat domains 1
  • Synonyms
    2810039F03Rik, 6330439K17Rik, Ankrd64
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139080
    NCBI Gene: 241688
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:144312477-144369334 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 71.02 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1859 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139080
 protein coding gene Chr2:144312475-144369427 (-)
129S1/SvImJ ENSMUSG00200007073
 protein coding gene Chr2:141379317-141436784 (-)
A/J ENSMUSG00195015529
 protein coding gene Chr2:141556308-141613162 (-)
AKR/J ENSMUSG00220037455
 protein coding gene Chr2:141097772-141154634 (-)
BALB/cJ ENSMUSG00180026433
 protein coding gene Chr2:141212629-141269485 (-)
C3H/HeJ ENSMUSG00175032340
 protein coding gene Chr2:141759762-141816613 (-)
C57BL/6NJ ENSMUSG00215019739
 protein coding gene Chr2:141268594-141325449 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024384
 protein coding gene Chr2:136730527-136788365 (-)
CAST/EiJ ENSTCUG00005010866
 protein coding gene Chr2:140414338-140471239 (-)
CBA/J ENSMUSG00210038494
 protein coding gene Chr2:141678991-141735848 (-)
DBA/2J ENSMUSG00185040208
 protein coding gene Chr2:141257644-141315108 (-)
FVB/NJ ENSMUSG00205024390
 protein coding gene Chr2:140442451-140498656 (-)
JF1/MsJ ENSUMUG00000027364
 protein coding gene Chr2:141058492-141115988 (-)
LP/J ENSMUSG00230007438
 protein coding gene Chr2:142961461-143019565 (-)
NOD/ShiLtJ ENSMUSG00190032307
 protein coding gene Chr2:141351235-141408096 (-)
NZO/HlLtJ ENSMUSG00225000977
 protein coding gene Chr2:150949581-151007685 (-)
PWK/PhJ ENSLUMG00010040148
 protein coding gene Chr2:141100789-141158309 (-)
SPRET/EiJ ENSMSPG00010025807
 protein coding gene Chr2:143585029-143642292 (-)
WSB/EiJ ENSIUOG00005023207
 protein coding gene Chr2:141124158-141180888 (-)



Homology
more
  • Human Ortholog
    DZANK1, double zinc ribbon and ankyrin repeat domains 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DZANK1, double zinc ribbon and ankyrin repeat domains 1
  • Synonyms
    ANKRD64, C20orf12, C20orf84
  • Links
    NCBI Gene ID: 55184
    UniProt: Q9NVP4

  • Chr Location
    20p11.23; chr20:18383361-18467332 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    630
  • Tissues
    13
  • cDNA Data
    38
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037259 Ensembl Gene Model | MGI Sequence Detail 56858 C57BL/6J ±  kb
    transcript ENSMUST00000163701 Ensembl | MGI Sequence Detail 6834 Not Applicable  
    polypeptide ENSMUSP00000133177 Ensembl | MGI Sequence Detail 779 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000032269 double zinc ribbon and ankyrin repeat-containing protein 1
      (term hierarchy)
    • InterPro Domains
      IPR002110 Ankyrin repeat
      IPR036770 Ankyrin repeat-containing domain superfamily
      IPR025874 Double zinc ribbon
      IPR052481 Double zinc ribbon and ankyrin repeat-containing protein 1
      IPR026876 Fn3 associated repeat
    • GlyGen
      Q8C008 1 site, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 38

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1919971
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 15
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory