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Ifi209 Gene Detail
Summary
  • Symbol
    Ifi209
  • Name
    interferon activated gene 209
  • Synonyms
    Ifix, Pyhin-1, Pyhin1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138243
    NCBI Gene: 236312
  • Alliance
    genome feature page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173458483-173475494 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 80.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    582 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138243
 protein coding gene Chr1:173458425-173475494 (+)
129S1/SvImJ ENSMUSG00200043763
 protein coding gene Chr1:171416660-171433567 (+)
A/J no annotation
AKR/J ENSMUSG00220029246
 protein coding gene Chr1:170442805-170459712 (+)
BALB/cJ ENSMUSG00180044967
 protein coding gene Chr1:170965581-170982488 (+)
C3H/HeJ ENSMUSG00175046381
 protein coding gene Chr1:171056245-171073152 (+)
C57BL/6NJ ENSMUSG00215042566
 protein coding gene Chr1:170419001-170436012 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014920
 protein coding gene Chr1:163966629-163982825 (-)
CAST/EiJ ENSTCUG00005045612
 protein coding gene Chr1:169008231-169025247 (+)
CBA/J ENSMUSG00210040768
 protein coding gene Chr1:170839352-170856257 (+)
DBA/2J ENSMUSG00185026956
 protein coding gene Chr1:175221300-175238207 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000010167
 protein coding gene Chr1:174133496-174150522 (+)
LP/J ENSMUSG00230031625
 protein coding gene Chr1:174827834-174835406 (+)
NOD/ShiLtJ ENSMUSG00190026172
 protein coding gene Chr1:170731706-170748613 (+)
NZO/HlLtJ ENSMUSG00225004533
 protein coding gene Chr1:178402064-178409636 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005036282
 protein coding gene Chr1:170028082-170044989 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    1
  • cDNA Data
    81
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043263 Ensembl Gene Model | MGI Sequence Detail 17012 C57BL/6J ±  kb
transcript ENSMUST00000056071 Ensembl | MGI Sequence Detail 3439 Not Applicable  
polypeptide ENSMUSP00000061900 Ensembl | MGI Sequence Detail 420 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR004020 DAPIN domain
    IPR011029 Death-like domain superfamily
    IPR040205 HIN-200 family
    IPR004021 HIN-200/IF120x
    IPR012340 Nucleic acid-binding, OB-fold
  • GlyGen
    Q8BV49 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 81
    cDNA 81

    Microarray probesets 4
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:359312 Jena KK, et al., Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair. Cell. 2024 Nov 4;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory