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Hemgn Gene Detail
Summary
  • Symbol
    Hemgn
  • Name
    hemogen
  • Synonyms
    4921524M03Rik, EDAG
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136910
    NCBI Gene: 93966
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:46393989-46404183 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 24.73 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    349 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136910
 protein coding gene Chr4:46393989-46413506 (-)
129S1/SvImJ ENSMUSG00200003125
 protein coding gene Chr4:42449691-42469226 (-)
A/J ENSMUSG00195006397
 protein coding gene Chr4:42903554-42923072 (-)
AKR/J ENSMUSG00220002544
 protein coding gene Chr4:42595645-42615169 (-)
BALB/cJ ENSMUSG00180027368
 protein coding gene Chr4:42490229-42509747 (-)
C3H/HeJ ENSMUSG00175020806
 protein coding gene Chr4:42639682-42659190 (-)
C57BL/6NJ ENSMUSG00215013854
 protein coding gene Chr4:42418861-42438379 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025986
 protein coding gene Chr4:40444920-40465150 (-)
CAST/EiJ ENSTCUG00005035372
 protein coding gene Chr4:42664943-42685143 (-)
CBA/J ENSMUSG00210019295
 protein coding gene Chr4:42326639-42346168 (-)
DBA/2J ENSMUSG00185032876
 protein coding gene Chr4:42690039-42709550 (-)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000017786
 protein coding gene Chr4:42909207-42928776 (-)
LP/J ENSMUSG00230039016
 protein coding gene Chr4:46250641-46270181 (-)
NOD/ShiLtJ ENSMUSG00190021256
 protein coding gene Chr4:42553691-42573220 (-)
NZO/HlLtJ ENSMUSG00225005971
 protein coding gene Chr4:50846487-50866009 (-)
PWK/PhJ ENSLUMG00010012029
 protein coding gene Chr4:41923901-41943423 (-)
SPRET/EiJ ENSMSPG00010008455
 protein coding gene Chr4:42838954-42858986 (-)
WSB/EiJ ENSIUOG00005004172
 protein coding gene Chr4:42302623-42322097 (-)



Homology
more
  • Human Ortholog
    HEMGN, hemogen
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HEMGN, hemogen
  • Synonyms
    CT155, EDAG, EDAG-1, NDR
  • Links
    NCBI Gene ID: 55363
    UniProt: Q9BXL5

  • Chr Location
    9q22.33; chr9:97926791-97944856 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced embryo and fetal size, reduced fetal liver weight, decreased erythroblast number, and impaired erythroid differentiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    62
  • cDNA Data
    37
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 93966 NCBI Gene Model | MGI Sequence Detail 10195 C57BL/6J ±  kb
    transcript NM_053149 RefSeq | MGI Sequence Detail 2310 C57BL/6  
    polypeptide Q9ERZ0 UniProt | EBI | MGI Sequence Detail 503 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 38
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1913968, MGI:2140231
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 7
      Gene Ontology 7
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory