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Abtb1 Gene Detail
Summary
  • Symbol
    Abtb1
  • Name
    ankyrin repeat and BTB domain containing 1
  • Synonyms
    BPOZ, EF1ABP, MGC:7237
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933148
    NCBI Gene: 80283
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:88812896-88818966 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 39.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933148
 protein coding gene Chr6:88812896-88819334 (-)
129S1/SvImJ ENSMUSG00200042235
 protein coding gene Chr6:85756966-85757276 (-)
129S1/SvImJ ENSMUSGG00200054553
 protein coding gene Chr6:85756966-85760105 (-)
A/J ENSMUSGG00195054984
 protein coding gene Chr6:85465555-85468694 (-)
A/J ENSMUSG00195039526
 protein coding gene Chr6:85465555-85465865 (-)
AKR/J ENSMUSGG00220054863
 protein coding gene Chr6:84359116-84362255 (-)
AKR/J ENSMUSG00220027000
 protein coding gene Chr6:84359116-84359426 (-)
BALB/cJ ENSMUSG00180015129
 protein coding gene Chr6:85838029-85838339 (-)
BALB/cJ ENSMUSGG00180055148
 protein coding gene Chr6:85838029-85841168 (-)
C3H/HeJ ENSMUSG00175035687
 protein coding gene Chr6:91564429-91564739 (+)
C3H/HeJ ENSMUSGG00175054831
 protein coding gene Chr6:91561600-91564739 (+)
C57BL/6NJ ENSMUSGG00215055793
 protein coding gene Chr6:85846936-85850075 (-)
C57BL/6NJ ENSMUSG00215012611
 protein coding gene Chr6:85846936-85847246 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028632
 protein coding gene Chr6:84932701-84938815 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054645
 protein coding gene Chr6:85655603-85658742 (-)
CBA/J ENSMUSG00210040671
 protein coding gene Chr6:85655603-85655913 (-)
DBA/2J ENSMUSG00185036383
 protein coding gene Chr6:86202849-86203159 (-)
DBA/2J ENSMUSGG00185057532
 protein coding gene Chr6:86202849-86205988 (-)
FVB/NJ ENSMUSG00205036389
 protein coding gene Chr6:84829130-84829440 (-)
FVB/NJ ENSMUSGG00205054217
 protein coding gene Chr6:84829130-84832269 (-)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055351
 protein coding gene Chr6:87337674-87340813 (-)
LP/J ENSMUSG00230048650
 protein coding gene Chr6:87337674-87337984 (-)
NOD/ShiLtJ ENSMUSGG00190054704
 protein coding gene Chr6:85274738-85277877 (-)
NOD/ShiLtJ ENSMUSG00190036106
 protein coding gene Chr6:85274738-85275048 (-)
NZO/HlLtJ ENSMUSG00225018267
 protein coding gene Chr6:89303050-89303360 (-)
NZO/HlLtJ ENSMUSGG00225055587
 protein coding gene Chr6:89303050-89306189 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010037622
 protein coding gene Chr6:86682247-86688348 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ABTB1, ankyrin repeat and BTB domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABTB1, ankyrin repeat and BTB domain containing 1
  • Synonyms
    BPOZ, BPOZ-2, BTB3, BTBD21, EF1ABP, PP2259
  • Links
    NCBI Gene ID: 80325
    UniProt: Q969K4

  • Chr Location
    3q21.3; chr3:127672906-127680926 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    790
  • Tissues
    48
  • cDNA Data
    60
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030083 Ensembl Gene Model | MGI Sequence Detail 6071 C57BL/6J ±  kb
    transcript ENSMUST00000032169 Ensembl | MGI Sequence Detail 1845 Not Applicable  
    polypeptide ENSMUSP00000032169 Ensembl | MGI Sequence Detail 478 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 62
      cDNA 61
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2141493
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 4
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:62894 Alliel PM, et al., Myoneurin, a novel member of the BTB/POZ-zinc finger family highly expressed in human muscle. Biochem Biophys Res Commun. 2000 Jun 24;273(1):385-91
    • Latest
      J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory