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Tnfrsf22 Gene Detail
Summary
  • Symbol
    Tnfrsf22
  • Name
    tumor necrosis factor receptor superfamily, member 22
  • Synonyms
    2810028K06Rik, C130035G06Rik, mDcTrailr2, SOBa, Tnfrh2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930270
    NCBI Gene: 79202
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:143188543-143203398 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 88.27 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    468 from dbSNP Build 142
  • Strain Annotations
    28
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930270
 protein coding gene Chr7:143188540-143203412 (-)
129S1/SvImJ ENSMUSG00200040700
 protein coding gene Chr7:129755152-129756931 (-)
129S1/SvImJ ENSMUSG00200040705
 protein coding gene Chr7:129756572-129769999 (-)
A/J ENSMUSG00195001706
 protein coding gene Chr7:134238734-134252165 (-)
A/J ENSMUSG00195001705
 protein coding gene Chr7:134237314-134239093 (-)
AKR/J ENSMUSG00220028444
 protein coding gene Chr7:127720930-127734365 (-)
AKR/J ENSMUSG00220028423
 protein coding gene Chr7:127719510-127721289 (-)
BALB/cJ ENSMUSG00180039701
 protein coding gene Chr7:130926583-130940018 (-)
BALB/cJ ENSMUSG00180039693
 protein coding gene Chr7:130925163-130926942 (-)
C3H/HeJ ENSMUSG00175004022
 protein coding gene Chr7:131658158-131659937 (-)
C3H/HeJ ENSMUSG00175004025
 protein coding gene Chr7:131659578-131673007 (-)
C57BL/6NJ ENSMUSG00215043073
 protein coding gene Chr7:130925958-130939389 (-)
C57BL/6NJ ENSMUSG00215043063
 protein coding gene Chr7:130924538-130926317 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030744
 protein coding gene Chr7:145837373-145850400 (-)
CAST/EiJ ENSTCUG00005002845
 protein coding gene Chr7:134226498-134239831 (-)
CBA/J ENSMUSG00210003489
 protein coding gene Chr7:131416058-131417837 (-)
CBA/J ENSMUSG00210003490
 protein coding gene Chr7:131417478-131430901 (-)
DBA/2J ENSMUSG00185013534
 protein coding gene Chr7:135696107-135709542 (-)
DBA/2J ENSMUSG00185013528
 protein coding gene Chr7:135694687-135696466 (-)
FVB/NJ ENSMUSG00205001827
 protein coding gene Chr7:131338193-131351644 (-)
FVB/NJ ENSMUSG00205001824
 protein coding gene Chr7:131336773-131338552 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230006583
 protein coding gene Chr7:141857922-141859701 (-)
LP/J ENSMUSG00230006649
 protein coding gene Chr7:141859342-141872769 (-)
NOD/ShiLtJ ENSMUSG00190003903
 protein coding gene Chr7:131523541-131525320 (-)
NOD/ShiLtJ ENSMUSG00190003905
 protein coding gene Chr7:131524961-131538388 (-)
NZO/HlLtJ ENSMUSG00225049650
 protein coding gene Chr7:140068281-140081708 (-)
NZO/HlLtJ ENSMUSG00225049632
 protein coding gene Chr7:140066861-140068692 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010034025
 protein coding gene Chr7:131376465-131422077 (-)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    625
  • Tissues
    24
  • cDNA Data
    18
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000010751 Ensembl Gene Model | MGI Sequence Detail 14856 C57BL/6J ±  kb
transcript ENSMUST00000075588 Ensembl | MGI Sequence Detail 4170 Not Applicable  
polypeptide ENSMUSP00000075018 Ensembl | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016931 tumor necrosis factor receptor superfamily member 22
    (term hierarchy)
  • InterPro Domains
    IPR002156 Ribonuclease H domain
    IPR012337 Ribonuclease H-like superfamily
    IPR036397 Ribonuclease H superfamily
    IPR001368 TNFR/NGFR cysteine-rich region
    IPR034062 Tumor necrosis factor receptor 26, N-terminal
    IPR052491 Tumor necrosis factor receptor superfamily member 10
  • GlyGen
    Q9ER62 2 sites, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919925, MGI:2442527
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65815 Engemann S, et al., Sequence and functional comparison in the beckwith-wiedemann region: implications for a novel imprinting centre and extended imprinting. Hum Mol Genet. 2000 Nov 1;9(18):2691-706
  • Latest
    J:277990 Uysal H, et al., Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy. Int J Mol Sci. 2018 Jul 4;19(7):1959
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory