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Lenep Gene Detail
Summary
  • Symbol
    Lenep
  • Name
    lens epithelial protein
  • Synonyms
    Lep503
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930020
    NCBI Gene: 57275
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:89309203-89309957 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 39.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    11 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930020
 protein coding gene Chr3:89308295-89310100 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027436
 protein coding gene Chr3:89613745-89615550 (-)
A/J MGP_AJ_G0027400
 protein coding gene Chr3:86648060-86649865 (-)
AKR/J MGP_AKRJ_G0027364
 protein coding gene Chr3:88740721-88742526 (-)
BALB/cJ MGP_BALBcJ_G0027409
 protein coding gene Chr3:86615195-86617000 (-)
C3H/HeJ MGP_C3HHeJ_G0027151
 protein coding gene Chr3:88947028-88948833 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027855
 protein coding gene Chr3:92999947-93001752 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025207
 protein coding gene Chr3:82131269-82133074 (-)
CAST/EiJ MGP_CASTEiJ_G0026597
 protein coding gene Chr3:89303434-89305239 (-)
CBA/J MGP_CBAJ_G0027125
 protein coding gene Chr3:96188822-96190627 (-)
DBA/2J MGP_DBA2J_G0027263
 protein coding gene Chr3:86026395-86028200 (-)
FVB/NJ MGP_FVBNJ_G0027231
 protein coding gene Chr3:84368910-84370715 (-)
LP/J MGP_LPJ_G0027372
 protein coding gene Chr3:90693486-90695291 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027251
 protein coding gene Chr3:102398123-102399929 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027914
 protein coding gene Chr3:88499424-88501229 (-)
PWK/PhJ MGP_PWKPhJ_G0026331
 protein coding gene Chr3:85904434-85906225 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026150
 protein coding gene Chr3:87673941-87675728 (-)
WSB/EiJ MGP_WSBEiJ_G0026679
 protein coding gene Chr3:88888494-88890299 (-)



Homology
more
  • Human Ortholog
    LENEP, lens epithelial protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LENEP, lens epithelial protein
  • Synonyms
    LEP503
  • Links
    NCBI Gene ID: 55891
    neXtProt AC: NX_Q9Y5L5
    UniProt: Q9Y5L5

  • Chr Location
    1q21.3; chr1:154993586-154994321 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57275 NCBI Gene Model | MGI Sequence Detail 755 C57BL/6J ±  kb
transcript NM_020517 RefSeq | MGI Sequence Detail 668 ZRU/MplStud  
polypeptide Q9WVB6 UniProt | EBI | MGI Sequence Detail 61 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139870
References
more
  • Summaries
    All 21
    Diseases 1
    Phenotypes 5
  • Earliest
    J:60595 Wen Y, et al., A novel lens epithelium gene, LEP503, is highly conserved in different vertebrate species and is developmentally regulated in postnatal rat lens. Exp Eye Res. 2000 Feb;70(2):159-68
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory