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Asb3 Gene Detail
Summary
  • Symbol
    Asb3
  • Name
    ankyrin repeat and SOCS box-containing 3
  • Synonyms
    2400011J03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929749
    NCBI Gene: 65257
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:30904398-31052704 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 18.19 cM, cytoband A4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3783 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929749
 protein coding gene Chr11:30835416-31052704 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018118
 protein coding gene Chr11:29000834-29223757 (+)
A/J MGP_AJ_G0018091
 protein coding gene Chr11:27919655-28124019 (+)
AKR/J MGP_AKRJ_G0018055
 protein coding gene Chr11:28804850-29012963 (+)
BALB/cJ MGP_BALBcJ_G0018060
 protein coding gene Chr11:28124316-28329993 (+)
C3H/HeJ MGP_C3HHeJ_G0017873
 protein coding gene Chr11:28739761-28977209 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018511
 protein coding gene Chr11:29958937-30191853 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0017435
 protein coding gene Chr11:28828341-29032783 (+)
CBA/J MGP_CBAJ_G0017846
 protein coding gene Chr11:31402440-31620973 (+)
DBA/2J MGP_DBA2J_G0017956
 protein coding gene Chr11:27736891-27950898 (+)
FVB/NJ MGP_FVBNJ_G0017950
 protein coding gene Chr11:27531294-27738884 (+)
LP/J MGP_LPJ_G0018028
 protein coding gene Chr11:29244814-29456278 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017974
 protein coding gene Chr11:32460172-32699694 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018552
 protein coding gene Chr11:28903227-29133851 (+)
PWK/PhJ MGP_PWKPhJ_G0017217
 protein coding gene Chr11:27836222-28052727 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017011
 protein coding gene Chr11:28617039-28850255 (+)
WSB/EiJ MGP_WSBEiJ_G0017487
 protein coding gene Chr11:28591713-28812300 (+)



Homology
more
  • Human Ortholog
    ASB3, ankyrin repeat and SOCS box containing 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASB3, ankyrin repeat and SOCS box containing 3
  • Synonyms
    ASB-3
  • Links
    NCBI Gene ID: 51130
    neXtProt AC: NX_Q9Y575
    UniProt: Q9Y575

  • Chr Location
    2p16.2; chr2:53532672-53860160 (-)  GRCh38
  • Human Ortholog
    GPR75-ASB3, GPR75-ASB3 readthrough
  • Synonyms
    ASB-3, ASB3
  • Links
    NCBI Gene ID: 100302652
    neXtProt AC: NX_Q9Y575

  • Chr Location
    2p16.2; chr2:53532672-53860160 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    32
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 65257 NCBI Gene Model | MGI Sequence Detail 148307 C57BL/6J ±  kb
transcript NM_023906 RefSeq | MGI Sequence Detail 3225 ZRU/MplStud  
polypeptide Q9WV72 UniProt | EBI | MGI Sequence Detail 525 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 5
Other
Accession IDs
less
MGI:1926018
References
more
  • Summaries
    All 44
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:360452 Cheng M, et al., ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota. mBio. 2024 Sep 11;15(9):e0204324
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory