Vsig2 MGI Mouse Gene Detail - MGI:1928009 - V-set and immunoglobulin domain containing 2

Symbol

Vsig2
Name

V-set and immunoglobulin domain containing 2
Synonyms

1190004B15Rik, 2210413P10Rik, CTM, CTX

Feature Type

protein coding gene
IDs

MGI:1928009
NCBI Gene: 57276
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr9:37450551-37455501 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 20.78 cM, cytoband B
Mapping Data

3 experiments

SNPs within 2kb

57 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1928009	protein coding gene	Chr9:37450551-37455501 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034567	protein coding gene	Chr9:35538091-35543023 (+)
A/J	MGP_AJ_G0034546	protein coding gene	Chr9:34583722-34588773 (+)
AKR/J	MGP_AKRJ_G0034473	protein coding gene	Chr9:35342230-35347180 (+)
BALB/cJ	MGP_BALBcJ_G0034537	protein coding gene	Chr9:34421478-34426408 (+)
C3H/HeJ	MGP_C3HHeJ_G0034250	protein coding gene	Chr9:35775261-35780191 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0035059	protein coding gene	Chr9:36673932-36678874 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031985	protein coding gene	Chr9:33687508-33692430 (+)
CAST/EiJ	MGP_CASTEiJ_G0033571	protein coding gene	Chr9:35470195-35475106 (+)
CBA/J	MGP_CBAJ_G0034223	protein coding gene	Chr9:37936658-37941576 (+)
DBA/2J	MGP_DBA2J_G0034381	protein coding gene	Chr9:34631158-34636149 (+)
FVB/NJ	MGP_FVBNJ_G0034322	protein coding gene	Chr9:33883158-33888098 (+)
LP/J	MGP_LPJ_G0034466	protein coding gene	Chr9:35714663-35719467 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034368	protein coding gene	Chr9:39534829-39539767 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035078	protein coding gene	Chr9:35281065-35285991 (+)
PWK/PhJ	MGP_PWKPhJ_G0033277	protein coding gene	Chr9:34527222-34532211 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033111	protein coding gene	Chr9:35477531-35482484 (+)
WSB/EiJ	MGP_WSBEiJ_G0033687	protein coding gene	Chr9:35098344-35103278 (+)

Human Ortholog

VSIG2, V-set and immunoglobulin domain containing 2

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

VSIG2, V-set and immunoglobulin domain containing 2
Synonyms

2210413P10Rik, CTH, CTXL
Links

HGNC:17149

NCBI Gene ID: 23584

neXtProt AC: NX_Q96IQ7

UniProt: Q96IQ7
Chr Location

11q24.2; chr11:124747474-124752213 (-) GRCh38.p7

Alliance of Genome Resources

Vsig2 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: VSIG2
Gene Tree

Vsig2

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

7
Gene trapped

2
Targeted

5
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

9 strains or lines available

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All GO Annotations

2
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

707
Tissues

1
cDNA Data

8
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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Vsig2 interacts with 13 markers (Mir218-1, Mir302b, Mir302c, ...) View All

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All Sequences

43
RefSeq

2
UniProt

3
CCDS

CCDS22980.1

Ensembl

ENSMUSG00000001943 (Evidence)
NCBI Gene

57276

			Length	Strain/Species	Flank
genomic	57276	NCBI Gene Model \| MGI Sequence Detail	4951	C57BL/6J	± kb
transcript	NM_020518	RefSeq \| MGI Sequence Detail	1170	C57BL/6
polypeptide	Q9Z109	UniProt \| EBI \| MGI Sequence Detail	328	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000032670 V-set and immunoglobulin domain-containing protein 2

(term hierarchy)
InterPro Domains

IPR013098 Immunoglobulin I-set

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003599 Immunoglobulin subtype

IPR003598 Immunoglobulin subtype 2

IPR013106 Immunoglobulin V-set domain

IPR042475 V-set and immunoglobulin domain-containing protein 2

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All nucleic 9

cDNA 8

Other 1

Microarray probesets 3

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MGI:1916153, MGI:1919617, MGI:2143229

Summaries

All 30

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 7
Earliest

J:64925 Chretien I, et al., CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates. Eur J Immunol. 1998 Dec;28(12):4094-104
Latest

J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

TSS for Vsig2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr84399	Chr9:37450561-37450575 (+)	17 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Copyright, and Privacy Statement Send questions and comments to User Support.	last database update 05/30/2023 MGI 6.22