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Rplp0 Gene Detail
Summary
  • Symbol
    Rplp0
  • Name
    ribosomal protein lateral stalk subunit P0
  • Synonyms
    36B4, Arbp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927636
    NCBI Gene: 11837
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:115697526-115701786 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 56.10 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927636
protein coding gene Chr5:115697526-115701788 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029973
protein coding gene Chr5:118457697-118465032 (+)
A/J MGP_AJ_G0029937
protein coding gene Chr5:113735842-113742037 (+)
AKR/J MGP_AKRJ_G0029876
protein coding gene Chr5:117381480-117385448 (+)
BALB/cJ MGP_BALBcJ_G0029948
protein coding gene Chr5:115130981-115141309 (+)
C3H/HeJ MGP_C3HHeJ_G0029668
protein coding gene Chr5:117897525-117902557 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030403
protein coding gene Chr5:123011851-123016408 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027630
protein coding gene Chr5:108509059-108513031 (+)
CAST/EiJ MGP_CASTEiJ_G0029077
protein coding gene Chr5:116840566-116848143 (+)
CBA/J MGP_CBAJ_G0029636
protein coding gene Chr5:127743192-127749113 (+)
DBA/2J MGP_DBA2J_G0029786
protein coding gene Chr5:113824407-113828443 (+)
FVB/NJ MGP_FVBNJ_G0029742
protein coding gene Chr5:112641649-112646677 (+)
LP/J MGP_LPJ_G0029874
protein coding gene Chr5:119014820-119020112 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029773
protein coding gene Chr5:132043737-132049188 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030444
protein coding gene Chr5:116858880-116862807 (+)
PWK/PhJ MGP_PWKPhJ_G0028790
protein coding gene Chr5:112469424-112474535 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028628
protein coding gene Chr5:114403865-114408095 (+)
WSB/EiJ MGP_WSBEiJ_G0029152
protein coding gene Chr5:117456222-117462561 (+)



Homology
more
  • Human Ortholog
    RPLP0, ribosomal protein lateral stalk subunit P0
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPLP0, ribosomal protein lateral stalk subunit P0
  • Synonyms
    L10E, LP0, P0, PRLP0, RPP0, uL10
  • Links
    NCBI Gene ID: 6175
    neXtProt AC: NX_P05388
    UniProt: P05388

  • Chr Location
    12q24.23; chr12:120196699-120201235 (-)  GRCh38

  • Human Ortholog
    RPLP0P6, ribosomal protein lateral stalk subunit P0 pseudogene 6
  • Synonyms
    RPLP0_2_209
  • Links
    NCBI Gene ID: 220717
    UniProt: Q8NHW5

  • Chr Location
    2p22.1; chr2:38481775-38482875 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067274 Ensembl Gene Model | MGI Sequence Detail 4261 C57BL/6J ±  kb
transcript ENSMUST00000086519 Ensembl | MGI Sequence Detail 1358 Not Applicable  
polypeptide ENSMUSP00000083705 Ensembl | MGI Sequence Detail 317 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000014237 eukaryotic-type large ribosomal subunit protein uL10
  • PDB
  • InterPro Domains
    IPR001790 Large ribosomal subunit protein uL10
    IPR030670 Large ribosomal subunit protein uL10, eukaryotes
    IPR043141 Large ribosomal subunit protein uL10-like domain superfamily
    IPR040637 Large ribosomal subunit protein uL10-like, insertion domain
    IPR043164 Large ribosomal subunit protein uL10-like, insertion domain superfamily
Molecular
Reagents
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  • All nucleic 32
    cDNA 25
    Primer pair 6
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-1386, MGI:88066
References
more
  • Summaries
    All 67
    Developmental Gene Expression 18
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory