About   Help   FAQ
Tmem131 Gene Detail
Summary
  • Symbol
    Tmem131
  • Name
    transmembrane protein 131
  • Synonyms
    2610524E03Rik, CC28, D1Bwg0491e, mKIAA0257, Neg, Rw1, YR-23
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927110
    NCBI Gene: 56030
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36831270-36978714 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 15.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1217 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927110
 protein coding gene Chr1:36831270-36982747 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015933
 protein coding gene Chr1:35358446-35514888 (-)
A/J MGP_AJ_G0015917
 protein coding gene Chr1:34402666-34554047 (-)
AKR/J MGP_AKRJ_G0015872
 protein coding gene Chr1:34884875-35037485 (-)
BALB/cJ MGP_BALBcJ_G0015871
 protein coding gene Chr1:34081312-34238015 (-)
C3H/HeJ MGP_C3HHeJ_G0015704
 protein coding gene Chr1:35089793-35245966 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016324
 protein coding gene Chr1:36945788-37102706 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014046
 protein coding gene Chr1:31443017-31596331 (-)
CAST/EiJ MGP_CASTEiJ_G0015285
 protein coding gene Chr1:34974309-35130619 (-)
CBA/J MGP_CBAJ_G0015676
 protein coding gene Chr1:37933845-38096015 (-)
DBA/2J MGP_DBA2J_G0015777
 protein coding gene Chr1:33733618-33886993 (-)
FVB/NJ MGP_FVBNJ_G0015779
 protein coding gene Chr1:33258241-33411568 (-)
LP/J MGP_LPJ_G0015847
 protein coding gene Chr1:35723258-35877187 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015799
 protein coding gene Chr1:40123258-40290740 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016371
 protein coding gene Chr1:34933869-35087332 (-)
PWK/PhJ MGP_PWKPhJ_G0015068
 protein coding gene Chr1:33491926-33646420 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014850
 protein coding gene Chr1:34875344-35039611 (-)
WSB/EiJ MGP_WSBEiJ_G0015347
 protein coding gene Chr1:34888343-35045843 (-)



Homology
more
  • Human Ortholog
    TMEM131, transmembrane protein 131
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM131, transmembrane protein 131
  • Synonyms
    CC28, PRO1048, RW1, YR-23
  • Links
    NCBI Gene ID: 23505
    neXtProt AC: NX_Q92545
    UniProt: Q92545

  • Chr Location
    2q11.2; chr2:97756333-97995948 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56030 NCBI Gene Model | MGI Sequence Detail 147445 C57BL/6J ±  kb
    transcript NM_018872 RefSeq | MGI Sequence Detail 6563 ZRU/MplStud  
    polypeptide O70472 UniProt | EBI | MGI Sequence Detail 1877 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 12
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-34271, MGI:106577, MGI:1917288
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 1
      Phenotypes 14
    • Earliest
      J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory