Avl9 MGI Mouse Gene Detail - MGI:1926187 - AVL9 cell migration associated

Symbol

Avl9
Name

AVL9 cell migration associated
Synonyms

5830411G16Rik, D730049P16Rik, mKIAA0241

Feature Type

protein coding gene
IDs

MGI:1926187
NCBI Gene: 78937
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr6:56691884-56738897 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 27.72 cM, cytoband C1
Mapping Data

2 experiments

SNPs within 2kb

249 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1926187	protein coding gene	Chr6:56691720-56738897 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0030780	protein coding gene	Chr6:56175638-56219063 (+)
A/J	MGP_AJ_G0030749	protein coding gene	Chr6:53570203-53615762 (+)
AKR/J	MGP_AKRJ_G0030676	protein coding gene	Chr6:55367642-55410218 (+)
BALB/cJ	MGP_BALBcJ_G0030761	protein coding gene	Chr6:53953691-53999325 (+)
C3H/HeJ	MGP_C3HHeJ_G0030474	protein coding gene	Chr6:55418880-55469470 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0031216	protein coding gene	Chr6:57443448-57488143 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028422	protein coding gene	Chr6:51133279-51178756 (+)
CAST/EiJ	MGP_CASTEiJ_G0029877	protein coding gene	Chr6:55258338-55304822 (+)
CBA/J	MGP_CBAJ_G0030448	protein coding gene	Chr6:59803842-59854741 (+)
DBA/2J	MGP_DBA2J_G0030598	protein coding gene	Chr6:53452914-53500372 (+)
FVB/NJ	MGP_FVBNJ_G0030550	protein coding gene	Chr6:53047521-53093249 (+)
LP/J	MGP_LPJ_G0030683	protein coding gene	Chr6:56098732-56142682 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0030584	protein coding gene	Chr6:62249465-62298784 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031246	protein coding gene	Chr6:55341877-55384404 (+)
PWK/PhJ	MGP_PWKPhJ_G0029590	protein coding gene	Chr6:53135416-53181332 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0029424	protein coding gene	Chr6:54744576-54792656 (+)
WSB/EiJ	MGP_WSBEiJ_G0029954	protein coding gene	Chr6:55401012-55446046 (+)

Human Ortholog

AVL9, AVL9 cell migration associated

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

AVL9, AVL9 cell migration associated
Synonyms

KIAA0241
Links

HGNC:28994

NCBI Gene ID: 23080

neXtProt AC: NX_Q8NBF6

UniProt: Q8NBF6
Chr Location

7p14.3; chr7:32495426-32588726 (+) GRCh38

Alliance of Genome Resources

Avl9 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: AVL9
Gene Tree

Avl9

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Endonuclease-mediated

3
Gene trapped

1
Targeted

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

39 strains or lines available

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All GO Annotations

5
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development	DNA-templated transcription

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

815
Tissues

39
cDNA Data

11
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase avl9

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Avl9 interacts with 450 markers (Mir1a-1, Mir1a-2, Mir1b, ...) View All

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All Sequences

54
RefSeq

8
UniProt

3
CCDS

CCDS51789.1

Ensembl

ENSMUSG00000029787 (Evidence)
NCBI Gene

78937

			Length	Strain/Species	Flank
genomic	ENSMUSG00000029787	Ensembl Gene Model \| MGI Sequence Detail	47014	C57BL/6J	± kb
transcript	ENSMUST00000031805	Ensembl \| MGI Sequence Detail	6670	Not Applicable
polypeptide	ENSMUSP00000031805	Ensembl \| MGI Sequence Detail	649	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000004522 late secretory pathway protein AVL9

(term hierarchy)
InterPro Domains

IPR018307 AVL9/DENND6 domain

IPR037516 Tripartite DENN domain

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All nucleic 11

cDNA 11

Microarray probesets 5

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MGI:1915379

Summaries

All 32

Developmental Gene Expression 2

Gene Ontology 3

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Avl9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr56680	Chr6:56691806-56691838 (+)	-62 bp
Tssr56681	Chr6:56691851-56691868 (+)	-24 bp
Tssr56682	Chr6:56691876-56691936 (+)	22 bp
Tssr56683	Chr6:56691943-56691956 (+)	66 bp
Tssr1859	Chr6:56691991-56692000 (+)	112 bp
Tssr56684	Chr6:56723533-56723544 (+)	31,655 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/21/2023 MGI 6.22