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Fndc8 Gene Detail
Summary
  • Symbol
    Fndc8
  • Name
    fibronectin type III domain containing 8
  • Synonyms
    4930466G16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926169
    NCBI Gene: 78919
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:82782971-82791563 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 50.30 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926169
 protein coding gene Chr11:82782950-82791627 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018833
 protein coding gene Chr11:84174952-84189854 (+)
A/J MGP_AJ_G0018800
 protein coding gene Chr11:80940916-80950271 (+)
AKR/J MGP_AKRJ_G0018770
 protein coding gene Chr11:83367690-83381103 (+)
BALB/cJ MGP_BALBcJ_G0018773
 protein coding gene Chr11:81344882-81353994 (+)
C3H/HeJ MGP_C3HHeJ_G0018587
 protein coding gene Chr11:83402721-83411274 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019225
 protein coding gene Chr11:86696595-86707960 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016859
 protein coding gene Chr11:77904719-77913516 (+)
CAST/EiJ MGP_CASTEiJ_G0018142
 protein coding gene Chr11:83991057-84000768 (+)
CBA/J MGP_CBAJ_G0018558
 protein coding gene Chr11:90451511-90461650 (+)
DBA/2J MGP_DBA2J_G0018666
 protein coding gene Chr11:80516078-80524927 (+)
FVB/NJ MGP_FVBNJ_G0018655
 protein coding gene Chr11:80041329-80050351 (+)
LP/J MGP_LPJ_G0018736
 protein coding gene Chr11:84689975-84699551 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018682
 protein coding gene Chr11:90648629-90658117 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019265
 protein coding gene Chr11:83630270-83640182 (+)
PWK/PhJ MGP_PWKPhJ_G0017912
 protein coding gene Chr11:81337308-81346543 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017703
 protein coding gene Chr11:83253329-83262047 (+)
WSB/EiJ MGP_WSBEiJ_G0018194
 protein coding gene Chr11:83516456-83526773 (+)



Homology
more
  • Human Ortholog
    FNDC8, fibronectin type III domain containing 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FNDC8, fibronectin type III domain containing 8
  • Links
    NCBI Gene ID: 54752
    neXtProt AC: NX_Q8TC99
    UniProt: Q8TC99

  • Chr Location
    17q12; chr17:35121615-35130732 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78919 NCBI Gene Model | MGI Sequence Detail 8593 C57BL/6J ±  kb
transcript NM_030224 RefSeq | MGI Sequence Detail 2081 Not Specified  
polypeptide Q9D2H8 UniProt | EBI | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory