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Ftx Gene Detail
Summary
  • Symbol
    Ftx
  • Name
    Ftx transcript, Xist regulator, non-protein coding
  • Synonyms
    B230206F22Rik, Thcytx
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1926128
    NCBI Gene: 78878
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:102604516-102667360 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 46.21 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    642 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926128
 lncRNA gene ChrX:102592988-102667512 (-)
129S1/SvImJ ENSMUSG00200039714
 lncRNA gene ChrX:84369836-84432720 (-)
A/J ENSMUSG00195042012
 lncRNA gene ChrX:88124570-88187471 (-)
AKR/J ENSMUSG00220037774
 lncRNA gene ChrX:82792024-82854932 (-)
BALB/cJ ENSMUSG00180042558
 lncRNA gene ChrX:84801845-84864749 (-)
C3H/HeJ ENSMUSG00175046545
 lncRNA gene ChrX:88374662-88437561 (-)
C57BL/6NJ ENSMUSG00215047264
 lncRNA gene ChrX:84981575-85044466 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006879
 lincRNA gene ChrX:97781635-97843452 (-)
CAST/EiJ ENSTCUG00005043632
 lncRNA gene ChrX:85844866-85907373 (-)
CBA/J ENSMUSG00210043814
 lncRNA gene ChrX:85265496-85328396 (-)
DBA/2J ENSMUSG00185044315
 lncRNA gene ChrX:97704486-97767388 (-)
FVB/NJ ENSMUSG00205035364
 lncRNA gene ChrX:84346969-84409867 (-)
JF1/MsJ ENSUMUG00000044310
 lncRNA gene ChrX:118312545-118375076 (-)
LP/J ENSMUSG00230043037
 lncRNA gene ChrX:104403008-104465894 (-)
NOD/ShiLtJ ENSMUSG00190044022
 lncRNA gene ChrX:84423317-84491760 (-)
NZO/HlLtJ ENSMUSG00225046124
 lncRNA gene ChrX:109523158-109586037 (-)
PWK/PhJ ENSLUMG00010039452
 lncRNA gene ChrX:83627325-83689836 (-)
SPRET/EiJ ENSMSPG00010040930
 lncRNA gene ChrX:87831260-87893485 (-)
WSB/EiJ ENSIUOG00005045270
 lncRNA gene ChrX:84926616-84989489 (-)



Homology
more
  • Human Ortholog
    FTX, FTX transcript, XIST regulator
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FTX, FTX transcript, XIST regulator
  • Synonyms
    LINC00182, MIR374AHG, NCRNA00182
  • Links
    NCBI Gene ID: 100302692

  • Chr Location
    Xq13.2; chrX:73940435-74293574 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 2 alleles in 4 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit partially abnormal X-inactivation that results in microphthalmia in some homozygous and heterozygous female mice. Knockout leads to enlarged spleen and SLE-like immune phenotype.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    608
  • Tissues
    4
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      128
    • RefSeq
      2
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 78878 NCBI Gene Model | MGI Sequence Detail 62845 C57BL/6J ±  kb
    transcript NR_028380 RefSeq | MGI Sequence Detail 4387 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 6
      Primer pair 3
    Other
    Accession IDs
    less
    MGI:2148043
    References
    more
    • Summaries
      All 23
      Developmental Gene Expression 1
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:378077 Huret C, et al., Altered X-chromosome inactivation predisposes to autoimmunity. Sci Adv. 2024 May 3;10(18):eadn6537
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory