Nup50l Gene Detail

Summary

• Symbol
  Nup50l
• Name
  nucleoporin 50 like
• Synonyms
  1700123L14Rik

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:1925732
  NCBI Gene: 78482
• Alliance
  genome feature page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr6:96141484-96143186 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 44.69 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  145 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925732	protein coding gene	Chr6:96141478-96143224 (-)
129S1/SvImJ	ENSMUSG00200020224	protein coding gene	Chr6:93125107-93126853 (-)
A/J	ENSMUSG00195001898	protein coding gene	Chr6:92846857-92848603 (-)
AKR/J	ENSMUSG00220021581	protein coding gene	Chr6:91732422-91734168 (-)
BALB/cJ	ENSMUSG00180009464	protein coding gene	Chr6:93213453-93215199 (-)
C3H/HeJ	ENSMUSG00175023934	protein coding gene	Chr6:84210228-84211974 (+)
C57BL/6NJ	ENSMUSG00215009402	protein coding gene	Chr6:93217245-93218991 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028674	protein coding gene	Chr6:92157756-92159490 (-)
CAST/EiJ	ENSTCUG00005001085	protein coding gene	Chr6:93306523-93308261 (-)
CBA/J	ENSMUSG00210003608	protein coding gene	Chr6:93011700-93013446 (-)
DBA/2J	ENSMUSG00185025275	protein coding gene	Chr6:93515589-93517335 (-)
FVB/NJ	ENSMUSG00205011890	protein coding gene	Chr6:92184090-92185836 (-)
JF1/MsJ	ENSUMUG00000001060	protein coding gene	Chr6:92455953-92457736 (-)
LP/J	ENSMUSG00230011285	protein coding gene	Chr6:94679673-94681419 (-)
NOD/ShiLtJ	ENSMUSG00190002575	protein coding gene	Chr6:92616854-92618600 (-)
NZO/HlLtJ	ENSMUSG00225039151	protein coding gene	Chr6:96683858-96685604 (-)
PWK/PhJ	ENSLUMG00010028626	protein coding gene	Chr6:91902241-91904009 (-)
SPRET/EiJ	ENSMSPG00010018196	protein coding gene	Chr6:94245127-94246806 (-)
WSB/EiJ	ENSIUOG00005002633	protein coding gene	Chr6:93597963-93599709 (-)

Homology

• Human Ortholog
  NUP50, nucleoporin 50

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  NUP50, nucleoporin 50
  
• Synonyms
  NPAP60, NPAP60L
• Links
  HGNC:8065

  NCBI Gene ID: 10762

  UniProt: Q9UKX7

  
  
• Chr Location
  22q13.31; chr22:45163925-45188017 (+)  GRCh38

---

• MGI Vertebrate Homology
  Nup50l stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: NUP50
• Gene Tree
  Nup50l
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Genomic Mutations
  1 involving Nup50l
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  32 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  6

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  31
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000072878 (Evidence)
• NCBI Gene
  78482

Representative Sequences			Length	Strain/Species
genomic	78482	NCBI Gene Model | MGI Sequence Detail	1703	C57BL/6J
transcript	NR_003643	RefSeq | MGI Sequence Detail	1703	C57BL/6
polypeptide	Q3V2K7	UniProt | EBI | MGI Sequence Detail	440	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:7384680

References

• Summaries
  All 21

  Phenotypes 6
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376

TSS for Nup50l:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr62193	Chr6:96143192-96143239 (-)	-30 bp
Tssr62192	Chr6:96143176-96143189 (-)	3 bp