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Pgpep1l Gene Detail
Summary
  • Symbol
    Pgpep1l
  • Name
    pyroglutamyl-peptidase I-like
  • Synonyms
    C330024D12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925694
    NCBI Gene: 78444
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:67886358-67913981 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 37.47 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    979 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925694
 protein coding gene Chr7:67881154-67914232 (-)
129S1/SvImJ ENSMUSG00200010773
 protein coding gene Chr7:54593813-54628578 (-)
A/J ENSMUSG00195012586
 protein coding gene Chr7:59018326-59053105 (-)
AKR/J ENSMUSG00220019895
 protein coding gene Chr7:52519140-52553910 (-)
BALB/cJ ENSMUSG00180004535
 protein coding gene Chr7:55728293-55763057 (-)
C3H/HeJ ENSMUSG00175010573
 protein coding gene Chr7:56520791-56555547 (-)
C57BL/6NJ ENSMUSG00215011993
 protein coding gene Chr7:55663584-55691211 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029854
 protein coding gene Chr7:70936032-70966350 (-)
CAST/EiJ ENSTCUG00005012079
 protein coding gene Chr7:59205669-59234223 (-)
CBA/J ENSMUSG00210019832
 protein coding gene Chr7:56359239-56394002 (-)
DBA/2J ENSMUSG00185000892
 protein coding gene Chr7:60702207-60729824 (-)
FVB/NJ ENSMUSG00205004386
 protein coding gene Chr7:56361390-56389035 (-)
JF1/MsJ ENSUMUG00000006837
 protein coding gene Chr7:65425075-65452352 (-)
LP/J ENSMUSG00230019905
 protein coding gene Chr7:66784040-66811664 (-)
NOD/ShiLtJ ENSMUSG00190007128
 protein coding gene Chr7:56467530-56502294 (-)
NZO/HlLtJ ENSMUSG00225015737
 protein coding gene Chr7:65059224-65092419 (-)
PWK/PhJ ENSLUMG00010018540
 protein coding gene Chr7:54983657-55010599 (-)
SPRET/EiJ ENSMSPG00010003088
 protein coding gene Chr7:55339950-55376888 (-)
WSB/EiJ ENSIUOG00005004619
 protein coding gene Chr7:56917670-56950963 (-)



Homology
more
  • Human Ortholog
    PGPEP1L, pyroglutamyl-peptidase I like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PGPEP1L, pyroglutamyl-peptidase I like
  • Links
    NCBI Gene ID: 145814
    UniProt: A6NFU8

  • Chr Location
    15q26.3; chr15:98966720-99007792 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    4
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Pgpep1l
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    18 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030553 Ensembl Gene Model | MGI Sequence Detail 27624 C57BL/6J ±  kb
transcript ENSMUST00000207874 Ensembl | MGI Sequence Detail 677 Not Applicable  
polypeptide ENSMUSP00000146996 Ensembl | MGI Sequence Detail 206 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Phenotypes 14
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory