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Flicr Gene Detail
Summary
  • Symbol
    Flicr
  • Name
    Foxp3 regulating long intergenic noncoding RNA
  • Synonyms
    4930524L23Rik, Ppp1r3fos
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1925435
    NCBI Gene: 78185
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:7439839-7447255 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 3.41 cM, cytoband A1.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    157 from dbSNP Build 142
  • Strain Annotations
    29
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925435
 lncRNA gene ChrX:7439839-7447266 (+)
129S1/SvImJ ENSMUSG00200031762
 protein coding gene ChrX:2141340-2145397 (+)
129S1/SvImJ ENSMUSG00200034669
 lncRNA gene ChrX:2140455-2147880 (+)
A/J ENSMUSG00195041240
 lncRNA gene ChrX:2163404-2170830 (+)
A/J ENSMUSG00195037182
 protein coding gene ChrX:2164289-2168348 (+)
AKR/J ENSMUSG00220036581
 lncRNA gene ChrX:2146162-2153586 (+)
BALB/cJ ENSMUSG00180025803
 protein coding gene ChrX:2140912-2144973 (+)
BALB/cJ ENSMUSG00180030815
 lncRNA gene ChrX:2140027-2147456 (+)
C3H/HeJ ENSMUSG00175031509
 protein coding gene ChrX:2175987-2179885 (+)
C3H/HeJ ENSMUSG00175033739
 lncRNA gene ChrX:2175102-2182528 (+)
C57BL/6NJ ENSMUSG00215041783
 lncRNA gene ChrX:2838930-2846356 (+)
C57BL/6NJ ENSMUSG00215037664
 protein coding gene ChrX:2839815-2843873 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0004266
 antisense lncRNA gene ChrX:1714970-1722336 (+)
CAST/EiJ ENSTCUG00005034292
 lncRNA gene ChrX:2111672-2119099 (+)
CBA/J ENSMUSG00210034433
 protein coding gene ChrX:2192838-2196897 (+)
CBA/J ENSMUSG00210041770
 lncRNA gene ChrX:2191953-2199380 (+)
DBA/2J ENSMUSG00185027374
 protein coding gene ChrX:8809990-8814051 (+)
DBA/2J ENSMUSG00185029044
 lncRNA gene ChrX:8809105-8816534 (+)
FVB/NJ ENSMUSG00205022241
 protein coding gene ChrX:2186620-2190678 (+)
FVB/NJ ENSMUSG00205034417
 lncRNA gene ChrX:2185735-2193161 (+)
JF1/MsJ ENSUMUG00000042736
 lncRNA gene ChrX:22694755-22702174 (+)
LP/J ENSMUSG00230027304
 protein coding gene ChrX:13330236-13334293 (+)
LP/J ENSMUSG00230033553
 lncRNA gene ChrX:13329351-13336776 (+)
NOD/ShiLtJ ENSMUSG00190039848
 lncRNA gene ChrX:2161059-2168484 (+)
NZO/HlLtJ ENSMUSG00225045402
 protein coding gene ChrX:18595730-18599788 (+)
NZO/HlLtJ ENSMUSG00225046165
 lncRNA gene ChrX:18594845-18602271 (+)
PWK/PhJ ENSLUMG00010034780
 lncRNA gene ChrX:2155109-2162541 (+)
SPRET/EiJ ENSMSPG00010026556
 lncRNA gene ChrX:2191388-2198808 (+)
WSB/EiJ ENSIUOG00005034513
 lncRNA gene ChrX:16354096-16361521 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout mice of this negative regulator of Foxp3 show decreased susceptibility to autoimmune diabetes and reduced severity of insulitis.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
Sequences &
Gene Models
less
  • All Sequences
    43
  • RefSeq
    1
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 78185 NCBI Gene Model | MGI Sequence Detail 7417 C57BL/6J ±  kb
transcript NR_029473 RefSeq | MGI Sequence Detail 3456 C57BL/6  
polypeptide Q8BNV6 UniProt | EBI | MGI Sequence Detail 130 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
Other
Accession IDs
less
MGI:5901917
References
more
  • Summaries
    All 15
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:241346 Zemmour D, et al., Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3472-E3480
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory