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Spata31 Gene Detail
Summary
  • Symbol
    Spata31
  • Name
    spermatogenesis associated 31
  • Synonyms
    4930458L03Rik, Fam75a, Spata31a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925374
    NCBI Gene: 78124
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:65065220-65071008 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 34.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    214 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925374
 protein coding gene Chr13:65065220-65071009 (+)
129S1/SvImJ ENSMUSG00200011609
 protein coding gene Chr13:61185351-61191244 (+)
A/J ENSMUSG00195026977
 protein coding gene Chr13:61350666-61356545 (+)
AKR/J ENSMUSG00220034706
 protein coding gene Chr13:60427104-60432995 (+)
BALB/cJ ENSMUSG00180024739
 protein coding gene Chr13:61650158-61656017 (+)
C3H/HeJ ENSMUSG00175007762
 protein coding gene Chr13:61474159-61480048 (+)
C57BL/6NJ ENSMUSG00215005938
 protein coding gene Chr13:61476580-61482368 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018646
 protein coding gene Chr13:60225206-60230425 (+)
CAST/EiJ ENSTCUG00005011581
 protein coding gene Chr13:61812097-61817982 (+)
CBA/J ENSMUSG00210008799
 protein coding gene Chr13:61673623-61679516 (+)
DBA/2J ENSMUSG00185007949
 protein coding gene Chr13:62506221-62512112 (+)
FVB/NJ ENSMUSG00205023864
 protein coding gene Chr13:60655435-60661316 (+)
JF1/MsJ ENSUMUG00000017575
 protein coding gene Chr13:62135160-62140948 (+)
LP/J ENSMUSG00230031878
 protein coding gene Chr13:71861830-71867710 (+)
NOD/ShiLtJ ENSMUSG00190034924
 protein coding gene Chr13:61415583-61421470 (+)
NZO/HlLtJ ENSMUSG00225045534
 protein coding gene Chr13:65566852-65572745 (+)
PWK/PhJ ENSLUMG00010010232
 protein coding gene Chr13:60950183-60956041 (+)
SPRET/EiJ ENSMSPG00010029560
 protein coding gene Chr13:61224772-61230661 (+)
WSB/EiJ ENSIUOG00005019519
 protein coding gene Chr13:60144816-60150698 (+)



Homology
more
  • Human Ortholog
    SPATA31A1, SPATA31 subfamily A member 1
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA31A1, SPATA31 subfamily A member 1
  • Synonyms
    C9orf36, C9orf36A, FAM75A1, FAM75A2, SPATA31A2
  • Links
    NCBI Gene ID: 647060
    UniProt: Q5TZJ5

  • Chr Location
    9p12; chr9:39355667-39361962 (+)  GRCh38
  • Human Ortholog
    SPATA31A3, SPATA31 subfamily A member 3
  • Synonyms
    FAM75A3
  • Links
    NCBI Gene ID: 727830
    UniProt: Q5VYP0

  • Chr Location
    9q21.11; chr9:66986304-66992550 (-)  GRCh38
  • Human Ortholog
    SPATA31A5, SPATA31 subfamily A member 5
  • Synonyms
    FAM75A5
  • Links
    NCBI Gene ID: 727905
    UniProt: Q5VU36

  • Chr Location
    9q12; chr9:60914372-60920653 (+)  GRCh38
  • Human Ortholog
    SPATA31A6, SPATA31 subfamily A member 6
  • Synonyms
    FAM75A6
  • Links
    NCBI Gene ID: 389730
    UniProt: Q5VVP1

  • Chr Location
    9p11.2; chr9:42183659-42189887 (+)  GRCh38
  • Human Ortholog
    SPATA31A7, SPATA31 subfamily A member 7
  • Synonyms
    AEP1, C9orf36, C9orf36A, FAM75A4, FAM75A7, SPATA31A4
  • Links
    NCBI Gene ID: 26165
    UniProt: Q8IWB4

  • Chr Location
    9q12; chr9:61190036-61196280 (+)  GRCh38
  • Human Ortholog
    SPATA31C1, SPATA31 subfamily C member 1
  • Synonyms
    FAM75C1
  • Links
    NCBI Gene ID: 441452
    UniProt: P0DKV0

  • Chr Location
    9q22.1; chr9:87913936-87923657 (+)  GRCh38
  • Human Ortholog
    SPATA31C2, SPATA31 subfamily C member 2
  • Synonyms
    FAM75C2
  • Links
    NCBI Gene ID: 645961
    UniProt: B4DYI2

  • Chr Location
    9q22.1; chr9:88129305-88138475 (-)  GRCh38
  • Human Ortholog
    SPATA31E1, SPATA31 subfamily E member 1
  • Synonyms
    C9orf79, FAM75E1
  • Links
    NCBI Gene ID: 286234
    UniProt: Q6ZUB1

  • Chr Location
    9q22.1; chr9:87882877-87888903 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with loss of expression in the gonads display male infertility with oligoteratozoospermia, marked reduction in spermatid numbers, and premature release of germ cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000056223 Ensembl Gene Model | MGI Sequence Detail 5789 C57BL/6J ±  kb
    transcript ENSMUST00000070216 Ensembl | MGI Sequence Detail 3232 Not Applicable  
    polypeptide ENSMUSP00000097025 Ensembl | MGI Sequence Detail 1014 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR039509 SPATA31
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    References
    more
    • Summaries
      All 26
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:296898 Tonelli Gombalova Z, et al., Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. J Comp Neurol. 2020 Oct 15;528(15):2523-2550
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory