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Fimp1 Gene Detail
Summary
  • Symbol
    Fimp1
  • Name
    fertilization influencing membrane protein 1
  • Synonyms
    4930451I11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925368
    NCBI Gene: 78118
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126429640-126430712 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 69.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925368
 protein coding gene Chr7:126429640-126430811 (-)
129S1/SvImJ ENSMUSG00200024343
 protein coding gene Chr7:112941211-112942239 (-)
A/J ENSMUSG00195042786
 protein coding gene Chr7:117456730-117457758 (-)
AKR/J ENSMUSG00220020348
 protein coding gene Chr7:110889553-110890581 (-)
BALB/cJ ENSMUSG00180012688
 protein coding gene Chr7:114130407-114131435 (-)
C3H/HeJ ENSMUSG00175014169
 protein coding gene Chr7:114857902-114858930 (-)
C57BL/6NJ ENSMUSG00215022326
 protein coding gene Chr7:114137849-114138877 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030468
 protein coding gene Chr7:128850158-128851324 (-)
CAST/EiJ ENSTCUG00005046147
 protein coding gene Chr7:117353219-117354243 (-)
CBA/J ENSMUSG00210022778
 protein coding gene Chr7:114618971-114619999 (-)
DBA/2J ENSMUSG00185048779
 protein coding gene Chr7:118931832-118932860 (-)
FVB/NJ ENSMUSG00205018262
 protein coding gene Chr7:114577423-114578451 (-)
JF1/MsJ ENSUMUG00000021742
 protein coding gene Chr7:123985335-123986359 (-)
LP/J ENSMUSG00230052695
 protein coding gene Chr7:125041206-125042234 (-)
NOD/ShiLtJ ENSMUSG00190013053
 protein coding gene Chr7:114777973-114779001 (-)
NZO/HlLtJ ENSMUSG00225011869
 protein coding gene Chr7:123270655-123271683 (-)
PWK/PhJ ENSLUMG00010031279
 protein coding gene Chr7:113125269-113126297 (-)
SPRET/EiJ ENSMSPG00010009154
 protein coding gene Chr7:114396234-114397261 (-)
WSB/EiJ ENSIUOG00005023832
 protein coding gene Chr7:115479822-115480850 (-)



Homology
more
  • Human Ortholog
    FIMP1, fertilization-influencing membrane protein 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FIMP1, fertilization-influencing membrane protein 1
  • Synonyms
    C16orf92, FIMP
  • Links
    NCBI Gene ID: 146378
    UniProt: Q96LL3

  • Chr Location
    16p11.2; chr16:30023198-30027736 (+)  GRCh38
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 3 alleles in 2 genetic backgrounds
    61 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a null mutation display severely reduced fertility with impaired fertilization due to impaired fusion on sperm with oocytes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 78118 NCBI Gene Model | MGI Sequence Detail 1073 C57BL/6J ±  kb
    transcript NM_183131 RefSeq | MGI Sequence Detail 475 C57BL/6  
    polypeptide E9Q9R3 UniProt | EBI | MGI Sequence Detail 111 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR038813 Fertilization-influencing membrane protein
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:8327516
    References
    more
    • Summaries
      All 82
      Diseases 3
      Gene Ontology 4
      Phenotypes 61
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:389705 Hao L, et al., Heart rate and sleep history encode ultradian REM sleep timing. Curr Biol. 2026 Mar 23;36(6):1422-1434.e5
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory