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Msl2 Gene Detail
Summary
  • Symbol
    Msl2
  • Name
    MSL complex subunit 2
  • Synonyms
    E130103E02Rik, Msl2l1, Rnf184
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925103
    NCBI Gene: 77853
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:100956154-100981999 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 53.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    172 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925103
 protein coding gene Chr9:100956107-100981999 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035181
 protein coding gene Chr9:102559094-102585991 (+)
A/J MGP_AJ_G0035162
 protein coding gene Chr9:98923105-98952465 (+)
AKR/J MGP_AKRJ_G0035094
 protein coding gene Chr9:101334683-101358911 (+)
BALB/cJ MGP_BALBcJ_G0035155
 protein coding gene Chr9:98607469-98637883 (+)
C3H/HeJ MGP_C3HHeJ_G0034865
 protein coding gene Chr9:101766925-101792541 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035675
 protein coding gene Chr9:105486650-105517489 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032574
 protein coding gene Chr9:96561305-96586338 (+)
CAST/EiJ MGP_CASTEiJ_G0034176
 protein coding gene Chr9:101571437-101598500 (+)
CBA/J MGP_CBAJ_G0034833
 protein coding gene Chr9:109157917-109186522 (+)
DBA/2J MGP_DBA2J_G0034995
 protein coding gene Chr9:98411359-98436051 (+)
FVB/NJ MGP_FVBNJ_G0034943
 protein coding gene Chr9:97211649-97240116 (+)
LP/J MGP_LPJ_G0035071
 protein coding gene Chr9:102776816-102803483 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034982
 protein coding gene Chr9:111039573-111066310 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035697
 protein coding gene Chr9:101601760-101631917 (+)
PWK/PhJ MGP_PWKPhJ_G0033883
 protein coding gene Chr9:98647410-98671185 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033719
 protein coding gene Chr9:101649836-101675301 (+)
WSB/EiJ MGP_WSBEiJ_G0034296
 protein coding gene Chr9:101477599-101507952 (+)



Homology
more
  • Human Ortholog
    MSL2, MSL complex subunit 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MSL2, MSL complex subunit 2
  • Synonyms
    MSL-2, MSL2L1, RNF184
  • Links
    NCBI Gene ID: 55167
    neXtProt AC: NX_Q9HCI7
    UniProt: Q9HCI7

  • Chr Location
    3q22.3; chr3:136148917-136197241 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    3
  • cDNA Data
    11
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066415 Ensembl Gene Model | MGI Sequence Detail 25846 C57BL/6J ±  kb
transcript ENSMUST00000085177 Ensembl | MGI Sequence Detail 4889 Not Applicable  
polypeptide ENSMUSP00000082270 Ensembl | MGI Sequence Detail 577 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 8
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:344688 Sun Y, et al., MSL2 ensures biallelic gene expression in mammals. Nature. 2023 Dec;624(7990):173-181
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory