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Dcst1 Gene Detail
Summary
  • Symbol
    Dcst1
  • Name
    DC-STAMP domain containing 1
  • Synonyms
    A330106H01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925022
    NCBI Gene: 77772
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:89257526-89272560 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 39.08 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    336 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925022
 protein coding gene Chr3:89257526-89272560 (-)
129S1/SvImJ ENSMUSG00200037562
 protein coding gene Chr3:86112775-86127809 (-)
A/J ENSMUSG00195050633
 protein coding gene Chr3:86127784-86142825 (-)
AKR/J ENSMUSG00220048443
 protein coding gene Chr3:86082352-86097391 (-)
BALB/cJ ENSMUSG00180046640
 protein coding gene Chr3:86209834-86224872 (-)
C3H/HeJ ENSMUSG00175042918
 protein coding gene Chr3:86060415-86075453 (-)
C57BL/6NJ ENSMUSG00215048080
 protein coding gene Chr3:86500525-86515559 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025204
 protein coding gene Chr3:82080746-82095785 (-)
CAST/EiJ ENSTCUG00005043995
 protein coding gene Chr3:85576054-85591155 (-)
CBA/J ENSMUSG00210037733
 protein coding gene Chr3:86198058-86213096 (-)
DBA/2J ENSMUSG00185046753
 protein coding gene Chr3:86298297-86313332 (-)
FVB/NJ ENSMUSG00205047491
 protein coding gene Chr3:85122018-85137059 (-)
JF1/MsJ ENSUMUG00000029662
 protein coding gene Chr3:85906908-85921955 (-)
LP/J ENSMUSG00230031710
 protein coding gene Chr3:88334083-88349118 (-)
NOD/ShiLtJ ENSMUSG00190033789
 protein coding gene Chr3:86583074-86598322 (-)
NZO/HlLtJ ENSMUSG00225007534
 protein coding gene Chr3:91089369-91104407 (-)
PWK/PhJ ENSLUMG00010044463
 protein coding gene Chr3:85948763-85963801 (-)
SPRET/EiJ ENSMSPG00010048942
 protein coding gene Chr3:86811339-86826674 (-)
WSB/EiJ ENSIUOG00005049461
 protein coding gene Chr3:86604567-86619600 (-)



Homology
more
  • Human Ortholog
    DCST1, DC-STAMP domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCST1, DC-STAMP domain containing 1
  • Synonyms
    SNKY, SPE49
  • Links
    NCBI Gene ID: 149095
    UniProt: Q5T197

  • Chr Location
    1q21.3; chr1:155033806-155050930 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 77772 NCBI Gene Model | MGI Sequence Detail 15035 C57BL/6J ±  kb
    transcript NM_029974 RefSeq | MGI Sequence Detail 2342 C57BL/6  
    polypeptide Q059Y8 UniProt | EBI | MGI Sequence Detail 732 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 2
    References
    more
    • Summaries
      All 36
      Diseases 1
      Gene Ontology 9
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:366270 Inoue N, et al., Noncanonical phagocytosis-like SEAL establishes mammalian fertilization. Cell Rep. 2025 Apr 22;44(4):115463
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory