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Fbxo42 Gene Detail
Summary
  • Symbol
    Fbxo42
  • Name
    F-box protein 42
  • Synonyms
    6720460I06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924992
    NCBI Gene: 213499
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:140875224-140931373 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 73.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    321 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924992
protein coding gene Chr4:140875216-140931373 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029040
protein coding gene Chr4:144164714-144235464 (+)
A/J MGP_AJ_G0028999
protein coding gene Chr4:137913051-137971454 (+)
AKR/J MGP_AKRJ_G0028951
protein coding gene Chr4:141890382-141948012 (+)
BALB/cJ MGP_BALBcJ_G0029023
protein coding gene Chr4:138601007-138664538 (+)
C3H/HeJ MGP_C3HHeJ_G0028737
protein coding gene Chr4:142266825-142325591 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029464
protein coding gene Chr4:149217612-149278095 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026735
protein coding gene Chr4:130826876-130883847 (+)
CAST/EiJ MGP_CASTEiJ_G0028169
protein coding gene Chr4:140523139-140581945 (+)
CBA/J MGP_CBAJ_G0028701
protein coding gene Chr4:153520550-153584997 (+)
DBA/2J MGP_DBA2J_G0028851
protein coding gene Chr4:138304206-138364732 (+)
FVB/NJ MGP_FVBNJ_G0028818
protein coding gene Chr4:137409623-137470188 (+)
LP/J MGP_LPJ_G0028950
protein coding gene Chr4:144186290-144246407 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028844
protein coding gene Chr4:157365244-157426082 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029502
protein coding gene Chr4:142418511-142476596 (+)
PWK/PhJ MGP_PWKPhJ_G0027890
protein coding gene Chr4:135192683-135250983 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027715
protein coding gene Chr4:138234035-138296030 (+)
WSB/EiJ MGP_WSBEiJ_G0028247
protein coding gene Chr4:142698755-142757842 (+)



Homology
more
  • Human Ortholog
    FBXO42, F-box protein 42
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO42, F-box protein 42
  • Synonyms
    Fbx42, JFK
  • Links
    NCBI Gene ID: 54455
    neXtProt AC: NX_Q6P3S6
    UniProt: Q6P3S6

  • Chr Location
    1p36.13; chr1:16246840-16352480 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028920 Ensembl Gene Model | MGI Sequence Detail 56150 C57BL/6J ±  kb
    transcript ENSMUST00000030757 Ensembl | MGI Sequence Detail 5934 Not Applicable  
    polypeptide ENSMUSP00000030757 Ensembl | MGI Sequence Detail 717 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 105
      cDNA 105

      Microarray probesets 3
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Phenotypes 15
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    02/13/2024
    MGI 6.23
    The Jackson Laboratory