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Nxpe4 Gene Detail
Summary
  • Symbol
    Nxpe4
  • Name
    neurexophilin and PC-esterase domain family, member 4
  • Synonyms
    D930028F11Rik, Fam55d
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924792
    NCBI Gene: 244853
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:48073321-48311325 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 26.39 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2579 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924792
 protein coding gene Chr9:48073302-48311325 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034758
 protein coding gene Chr9:47147796-47173916 (+)
A/J MGP_AJ_G0034739
 protein coding gene Chr9:45740193-45775846 (+)
AKR/J MGP_AKRJ_G0034666
 protein coding gene Chr9:46710863-46734195 (+)
BALB/cJ MGP_BALBcJ_G0034730
 protein coding gene Chr9:45457153-45493366 (+)
C3H/HeJ MGP_C3HHeJ_G0034441
 protein coding gene Chr9:47166847-47187196 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035251
 protein coding gene Chr9:48457594-48507613 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032164
 protein coding gene Chr9:45224131-45259764 (+)
CAST/EiJ MGP_CASTEiJ_G0033763
 protein coding gene Chr9:47063759-47101094 (+)
CBA/J MGP_CBAJ_G0034413
 protein coding gene Chr9:50204638-50231472 (+)
DBA/2J MGP_DBA2J_G0034572
 protein coding gene Chr9:45592859-45632623 (+)
FVB/NJ MGP_FVBNJ_G0034513
 protein coding gene Chr9:44850443-44887185 (+)
LP/J MGP_LPJ_G0034653
 protein coding gene Chr9:47489630-47529512 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034557
 protein coding gene Chr9:51895516-51939112 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035272
 protein coding gene Chr9:46621178-46642925 (+)
PWK/PhJ MGP_PWKPhJ_G0033468
 protein coding gene Chr9:45548739-45586943 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033304
 protein coding gene Chr9:46926904-46964918 (+)
WSB/EiJ MGP_WSBEiJ_G0033876
 protein coding gene Chr9:46665619-46698871 (+)



Homology
more
  • Human Ortholog
    NXPE4, neurexophilin and PC-esterase domain family member 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NXPE4, neurexophilin and PC-esterase domain family member 4
  • Synonyms
    C11orf33, FAM55D
  • Links
    NCBI Gene ID: 54827
    neXtProt AC: NX_Q6UWF7
    UniProt: Q6UWF7

  • Chr Location
    11q23.2; chr11:114570591-114596215 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044229 Ensembl Gene Model | MGI Sequence Detail 238005 C57BL/6J ±  kb
transcript ENSMUST00000215780 Ensembl | MGI Sequence Detail 2875 Not Applicable  
polypeptide ENSMUSP00000149741 Ensembl | MGI Sequence Detail 543 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:139206 Tabakoff B, et al., The genomic determinants of alcohol preference in mice. Mamm Genome. 2008 May;19(5):352-65
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/30/2023
MGI 6.22 		The Jackson Laboratory