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Sccpdh Gene Detail
Summary
  • Symbol
    Sccpdh
  • Name
    saccharopine dehydrogenase (putative)
  • Synonyms
    C330023F11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924486
    NCBI Gene: 109232
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:179495796-179514754 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 83.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1128 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924486
 protein coding gene Chr1:179495775-179514754 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016861
 protein coding gene Chr1:186039129-186061122 (+)
A/J MGP_AJ_G0016840
 protein coding gene Chr1:178545151-178563921 (+)
AKR/J MGP_AKRJ_G0016806
 protein coding gene Chr1:183859567-183878118 (+)
BALB/cJ MGP_BALBcJ_G0016798
 protein coding gene Chr1:179172517-179193779 (+)
C3H/HeJ MGP_C3HHeJ_G0016623
 protein coding gene Chr1:184595375-184619907 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017261
 protein coding gene Chr1:192060261-192099728 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014969
 protein coding gene Chr1:169532950-169551972 (+)
CAST/EiJ MGP_CASTEiJ_G0016204
 protein coding gene Chr1:183913235-183931678 (+)
CBA/J MGP_CBAJ_G0016597
 protein coding gene Chr1:199222120-199248285 (+)
DBA/2J MGP_DBA2J_G0016703
 protein coding gene Chr1:177384406-177405979 (+)
FVB/NJ MGP_FVBNJ_G0016699
 protein coding gene Chr1:175469381-175488122 (+)
LP/J MGP_LPJ_G0016777
 protein coding gene Chr1:187313162-187334647 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016730
 protein coding gene Chr1:206353778-206378827 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017298
 protein coding gene Chr1:183592933-183611674 (+)
PWK/PhJ MGP_PWKPhJ_G0015992
 protein coding gene Chr1:176465428-176484958 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015768
 protein coding gene Chr1:182544140-182563173 (+)
WSB/EiJ MGP_WSBEiJ_G0016267
 protein coding gene Chr1:183820333-183839858 (+)



Homology
more
  • Human Ortholog
    SCCPDH, saccharopine dehydrogenase (putative)
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCCPDH, saccharopine dehydrogenase (putative)
  • Synonyms
    CGI-49, CGI49, NET11
  • Links
    NCBI Gene ID: 51097
    UniProt: Q8NBX0

  • Chr Location
    1q44; chr1:246724409-246768137 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    5
  • cDNA Data
    18
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 109232 NCBI Gene Model | MGI Sequence Detail 18959 C57BL/6J ±  kb
    transcript NR_184455 RefSeq | MGI Sequence Detail 2001 C57BL/6  
    polypeptide Q8R127 UniProt | EBI | MGI Sequence Detail 429 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000029749 saccharopine dehydrogenase-like oxidoreductase
      (term hierarchy)
    • EC
      1.-.-.-
    • InterPro Domains
      IPR036291 NAD(P)-binding domain superfamily
      IPR051276 Saccharopine dehydrogenase-like oxidoreductase
      IPR005097 Saccharopine dehydrogenase, NADP binding domain
    • GlyGen
      Q8R127 3 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2138579
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    03/25/2025
    MGI 6.24     		The Jackson Laboratory