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Bcl7a Gene Detail
Summary
  • Symbol
    Bcl7a
  • Name
    B cell CLL/lymphoma 7A
  • Synonyms
    4432415N06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924295
    NCBI Gene: 77045
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:123482511-123512146 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 62.92 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    760 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924295
protein coding gene Chr5:123481897-123513055 (+)
129S1/SvImJ ENSMUSG00200023054
protein coding gene Chr5:117203586-117234205 (+)
A/J ENSMUSG00195011642
protein coding gene Chr5:116725021-116755641 (+)
AKR/J ENSMUSG00220034996
protein coding gene Chr5:116238950-116269604 (+)
BALB/cJ ENSMUSG00180030716
protein coding gene Chr5:116839974-116870594 (+)
C3H/HeJ ENSMUSG00175028576
protein coding gene Chr5:118858785-118889442 (+)
C57BL/6NJ ENSMUSG00215023844
protein coding gene Chr5:116890692-116921368 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027724
protein coding gene Chr5:116341803-116373352 (+)
CAST/EiJ ENSTCUG00005039750
protein coding gene Chr5:116144512-116175469 (+)
CBA/J ENSMUSG00210009123
protein coding gene Chr5:117609524-117640183 (+)
DBA/2J ENSMUSG00185051918
protein coding gene Chr5:120660777-120691380 (+)
FVB/NJ ENSMUSG00205034143
protein coding gene Chr5:116520507-116551173 (+)
JF1/MsJ ENSUMUG00000013852
protein coding gene Chr5:123512215-123542996 (+)
LP/J ENSMUSG00230042189
protein coding gene Chr5:124725569-124756185 (+)
NOD/ShiLtJ ENSMUSG00190035290
protein coding gene Chr5:116535196-116565796 (+)
NZO/HlLtJ ENSMUSG00225012876
protein coding gene Chr5:132423603-132454269 (+)
PWK/PhJ ENSLUMG00010039363
protein coding gene Chr5:115414411-115445195 (+)
SPRET/EiJ ENSMSPG00010041567
protein coding gene Chr5:118719279-118747317 (+)
WSB/EiJ ENSIUOG00005014161
protein coding gene Chr5:119223251-119253858 (+)



Homology
more
  • Human Ortholog
    BCL7A, BAF chromatin remodeling complex subunit BCL7A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCL7A, BAF chromatin remodeling complex subunit BCL7A
  • Synonyms
    BCL7, SMARCJ1
  • Links
    NCBI Gene ID: 605
    UniProt: Q4VC05

  • Chr Location
    12q24.31; chr12:122019422-122062044 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 3 alleles in 3 genetic backgrounds
    9 phenotypes from multigenic genotypes
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for null alleles display preweaning lethality.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 77045 NCBI Gene Model | MGI Sequence Detail 29636 C57BL/6J ±  kb
    transcript NM_029850 RefSeq | MGI Sequence Detail 3809 C57BL/6  
    polypeptide Q9CXE2 UniProt | EBI | MGI Sequence Detail 210 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1
      Antibodies 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2140884
    References
    more
    • Summaries
      All 62
      Developmental Gene Expression 7
      Gene Ontology 17
      Phenotypes 22
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory