Fbxw27 Gene Detail

Summary

• Symbol
  Fbxw27
• Name
  F-box and WD-40 domain protein 27
• Synonyms
  1700124P09Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1924248
  NCBI Gene: 76998
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr9:109595113-109619738 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, 59.74 cM, cytoband F2
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  48 from dbSNP Build 142
• Strain Annotations
  13

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924248	protein coding gene	Chr9:109595045-109620484 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0007509	lincRNA gene	Chr9:111850531-111858387 (-)
A/J	no annotation
AKR/J	MGP_AKRJ_G0007476	lincRNA gene	Chr9:110474026-110508748 (-)
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	MGP_C57BL6NJ_G0007653	lincRNA gene	Chr9:114880922-114926750 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006834	lincRNA gene	Chr9:105060972-105068603 (-)
CAST/EiJ	MGP_CASTEiJ_G0007329	lincRNA gene	Chr9:110675315-110684777 (-)
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0007433	lincRNA gene	Chr9:107265656-107273521 (-)
FVB/NJ	MGP_FVBNJ_G0007449	lincRNA gene	Chr9:106083180-106091035 (-)
LP/J	MGP_LPJ_G0007513	lincRNA gene	Chr9:112128300-112136477 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0007658	lincRNA gene	Chr9:110785959-110793839 (-)
PWK/PhJ	MGP_PWKPhJ_G0007270	lincRNA gene	Chr9:107437901-107445757 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0007174	lincRNA gene	Chr9:110867636-110875310 (-)
WSB/EiJ	MGP_WSBEiJ_G0007389	lincRNA gene	Chr9:110566368-110574230 (-)

Homology

• Human Ortholog
  FBXW12, F-box and WD repeat domain containing 12

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FBXW12, F-box and WD repeat domain containing 12
  
• Synonyms
  FBW12, FBXO12, FBXO35
• Links
  HGNC:20729

  NCBI Gene ID: 285231

  neXtProt AC: NX_Q6X9E4

  UniProt: Q6X9E4

  
  
• Chr Location
  3p21.31; chr3:48372219-48401259 (+)  GRCh38

---

• MGI Vertebrate Homology
  Fbxw27 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: FBXW12
• Gene Tree
  Fbxw27
  

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  12

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  44
• RefSeq
  8
• UniProt
  4
• CCDS
  CCDS85731.1

• Ensembl
  ENSMUSG00000104614 (Evidence)
• NCBI Gene
  76998

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000104614	Ensembl Gene Model | MGI Sequence Detail	24626	C57BL/6J
transcript	ENSMUST00000212725	Ensembl | MGI Sequence Detail	1483	Not Applicable
polypeptide	ENSMUSP00000148340	Ensembl | MGI Sequence Detail	466	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• InterPro Domains
  IPR001810 F-box domain
  IPR036047 F-box-like domain superfamily
  IPR036322 WD40-repeat-containing domain superfamily
  IPR015943 WD40/YVTN repeat-like-containing domain superfamily

Molecular
Reagents

• All nucleic 12

  cDNA 12

  
  

  Microarray probesets 1

References

• Summaries
  All 14

  Gene Ontology 1
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573