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Sprr5 Gene Detail
Summary
  • Symbol
    Sprr5
  • Name
    small proline rich protein 5
  • Synonyms
    2310046K23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924218
    NCBI Gene: 76968
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92439812-92441818 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    201 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924218
protein coding gene Chr3:92439812-92441818 (-)
129S1/SvImJ ENSMUSG00200036811
protein coding gene Chr3:89227392-89229398 (-)
A/J ENSMUSG00195052555
protein coding gene Chr3:89237050-89239056 (-)
AKR/J ENSMUSG00220045553
protein coding gene Chr3:88457833-88459837 (-)
BALB/cJ ENSMUSG00180043874
protein coding gene Chr3:89403630-89405630 (-)
C3H/HeJ ENSMUSG00175046631
protein coding gene Chr3:89174876-89176882 (-)
C57BL/6NJ ENSMUSG00215045452
protein coding gene Chr3:89786230-89788237 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025269
protein coding gene Chr3:86695355-86697307 (-)
CAST/EiJ ENSTCUG00005044601
protein coding gene Chr3:89558959-89561043 (-)
CBA/J ENSMUSG00210040981
protein coding gene Chr3:89290076-89292082 (-)
DBA/2J ENSMUSG00185050594
protein coding gene Chr3:89493269-89495267 (-)
FVB/NJ ENSMUSG00205046410
protein coding gene Chr3:88258859-88260861 (-)
JF1/MsJ ENSUMUG00000027966
protein coding gene Chr3:89041303-89043344 (-)
LP/J ENSMUSG00230035390
protein coding gene Chr3:91524871-91526877 (-)
NOD/ShiLtJ ENSMUSG00190035443
protein coding gene Chr3:89620264-89622347 (-)
NZO/HlLtJ ENSMUSG00225008169
protein coding gene Chr3:94373947-94375945 (-)
PWK/PhJ ENSLUMG00010042755
protein coding gene Chr3:89101772-89103817 (-)
SPRET/EiJ ENSMSPG00010048847
protein coding gene Chr3:89560781-89562802 (-)
WSB/EiJ ENSIUOG00005049209
protein coding gene Chr3:89771213-89773292 (-)



Homology
more
  • Human Ortholog
    SPRR5, small proline rich protein 5
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPRR5, small proline rich protein 5
  • Links
    NCBI Gene ID: 110806278
    UniProt: A0A1B0GTR4

  • Chr Location
    1q21.3; chr1:152947206-152949255 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Sprr5
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000102308 Ensembl Gene Model | MGI Sequence Detail 2007 C57BL/6J ±  kb
transcript ENSMUST00000193521 Ensembl | MGI Sequence Detail 677 Not Applicable  
polypeptide ENSMUSP00000141296 Ensembl | MGI Sequence Detail 87 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:7461656
References
more
  • Summaries
    All 16
    Diseases 1
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/15/2026
MGI 6.29
The Jackson Laboratory