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Tsacc Gene Detail
Summary
  • Symbol
    Tsacc
  • Name
    TSSK6 activating co-chaperone
  • Synonyms
    1700021C14Rik, SIP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924177
    NCBI Gene: 76927
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:88190064-88204306 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 38.79 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    372 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924177
 protein coding gene Chr3:88190059-88204306 (-)
129S1/SvImJ ENSMUSG00200039307
 protein coding gene Chr3:85044924-85059168 (-)
A/J ENSMUSG00195050879
 protein coding gene Chr3:85066600-85080838 (-)
AKR/J ENSMUSG00220050417
 protein coding gene Chr3:85021660-85035898 (-)
BALB/cJ ENSMUSG00180039276
 protein coding gene Chr3:85191287-85205529 (-)
C3H/HeJ ENSMUSG00175034589
 protein coding gene Chr3:84999652-85013891 (-)
C57BL/6NJ ENSMUSG00215045816
 protein coding gene Chr3:85432644-85446892 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025159
 protein coding gene Chr3:81061411-81071857 (-)
CAST/EiJ ENSTCUG00005042638
 protein coding gene Chr3:84523087-84536161 (-)
CBA/J ENSMUSG00210034357
 protein coding gene Chr3:85137326-85151567 (-)
DBA/2J ENSMUSG00185047381
 protein coding gene Chr3:85279925-85294163 (-)
FVB/NJ ENSMUSG00205043320
 protein coding gene Chr3:84061505-84075728 (-)
JF1/MsJ ENSUMUG00000009395
 protein coding gene Chr3:84814353-84828504 (-)
LP/J ENSMUSG00230026059
 protein coding gene Chr3:87266321-87280563 (-)
NOD/ShiLtJ ENSMUSG00190038730
 protein coding gene Chr3:85513731-85527949 (-)
NZO/HlLtJ ENSMUSG00225005741
 protein coding gene Chr3:90028877-90043111 (-)
PWK/PhJ ENSLUMG00010040191
 protein coding gene Chr3:84904016-84918155 (-)
SPRET/EiJ ENSMSPG00010049860
 protein coding gene Chr3:85746454-85759865 (-)
WSB/EiJ ENSIUOG00005048198
 protein coding gene Chr3:85513673-85527693 (-)



Homology
more
  • Human Ortholog
    TSACC, TSSK6 activating cochaperone
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSACC, TSSK6 activating cochaperone
  • Synonyms
    C1orf182, SIP, SSTK-IP
  • Links
    NCBI Gene ID: 128229
    UniProt: Q96A04

  • Chr Location
    1q22; chr1:156337314-156346995 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    133
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    125
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Tsacc
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    151 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    33
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000010538 Ensembl Gene Model | MGI Sequence Detail 14243 C57BL/6J ±  kb
transcript ENSMUST00000107556 Ensembl | MGI Sequence Detail 584 Not Applicable  
polypeptide ENSMUSP00000103180 Ensembl | MGI Sequence Detail 124 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 2
References
more
  • Summaries
    All 43
    Diseases 1
    Gene Ontology 7
    Phenotypes 17
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:363654 Wang J, et al., Cortex-Specific Tmem169 Deficiency Induces Defects in Cortical Neuron Development and Autism-Like Behaviors in Mice. J Neurosci. 2025 Feb 26;45(9)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory