Rps9 MGI Mouse Gene Detail - MGI:1924096

Symbol

Rps9
Name

ribosomal protein S9
Synonyms

3010033P07Rik

Feature Type

protein coding gene
IDs

MGI:1924096
NCBI Gene: 76846
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr7:3707035-3709896 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 2.13 cM, cytoband A1
Mapping Data

3 experiments

SNPs within 2kb

305 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924096	protein coding gene	Chr7:3706992-3709896 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031530	protein coding gene	Chr7:633306-636249 (+)
A/J	MGP_AJ_G0031505	protein coding gene	Chr7:570292-573191 (+)
AKR/J	MGP_AKRJ_G0031433	protein coding gene	Chr7:586026-588932 (+)
BALB/cJ	MGP_BALBcJ_G0031513	protein coding gene	Chr7:585436-588851 (+)
C3H/HeJ	MGP_C3HHeJ_G0031233	protein coding gene	Chr7:593824-596774 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0031973	protein coding gene	Chr7:610167-613068 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029100	protein coding gene	Chr7:476010-478763 (+)
CAST/EiJ	MGP_CASTEiJ_G0030602	protein coding gene	Chr7:587614-590525 (+)
CBA/J	MGP_CBAJ_G0031193	protein coding gene	Chr7:737529-742029 (+)
DBA/2J	MGP_DBA2J_G0031350	protein coding gene	Chr7:569787-572697 (+)
FVB/NJ	MGP_FVBNJ_G0031302	protein coding gene	Chr7:562192-566005 (+)
LP/J	MGP_LPJ_G0031435	protein coding gene	Chr7:653317-656223 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031341	protein coding gene	Chr7:632182-636318 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032007	protein coding gene	Chr7:579606-582507 (+)
PWK/PhJ	MGP_PWKPhJ_G0030329	protein coding gene	Chr7:716365-719386 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030153	protein coding gene	Chr7:645085-647986 (+)
WSB/EiJ	MGP_WSBEiJ_G0030696	protein coding gene	Chr7:582143-585952 (+)

Human Ortholog

RPS9, ribosomal protein S9

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPS9, ribosomal protein S9
Synonyms

S9, uS4
Links

HGNC:10442

NCBI Gene ID: 6203

UniProt: P46781
Chr Location

19q13.42; chr19:54200809-54249003 (+) GRCh38

MGI Vertebrate Homology

Rps9 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPS9
Gene Tree

Rps9

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Phenotype Summary

20 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

29
Endonuclease-mediated

1
Gene trapped

24
Targeted

4
Incidental Mutations

CvDC
Find Mice (IMSR)

14 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a point mutation exhibit premature aging.

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All GO Annotations

21
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

756
Tissues

32
cDNA Data

702
Literature Summary

7

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rps9

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All Sequences

70
RefSeq

11
UniProt

7
CCDS

CCDS20726.1

Ensembl

ENSMUSG00000006333 (Evidence)
NCBI Gene

76846

			Length	Strain/Species	Flank
genomic	76846	NCBI Gene Model \| MGI Sequence Detail	2862	C57BL/6J	± kb
transcript	NR_185013	RefSeq \| MGI Sequence Detail	882	C57BL/6
polypeptide	Q6ZWN5	UniProt \| EBI \| MGI Sequence Detail	194	Not Applicable

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UniProt

7 Sequences
Protein Ontology

PR:000014292 eukaryotic-type small ribosomal subunit protein uS4

(term hierarchy)
PDB

7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR002942 RNA-binding S4 domain

IPR036986 RNA-binding S4 domain superfamily

IPR022801 Small ribosomal subunit protein uS4

IPR018079 Small ribosomal subunit protein uS4, conserved site

IPR005710 Small ribosomal subunit protein uS4, eukaryotic/archaeal

IPR001912 Small ribosomal subunit protein uS4, N-terminal
GlyGen

Q6ZWN5 2 sites, 1 O-linked glycan (1 site)

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All nucleic 704

cDNA 702

Primer pair 2

Microarray probesets 3

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MGI:2142087, MGI:2142089

Summaries

All 42

Developmental Gene Expression 7

Gene Ontology 4

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:329923 Brilkova M, et al., Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice. Cell Rep. 2022 Sep 27;40(13):111433

TSS for Rps9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr64287	Chr7:3706978-3707023 (+)	-34 bp
Tssr64288	Chr7:3707024-3707050 (+)	2 bp
Tssr64289	Chr7:3707198-3707247 (+)	188 bp
Tssr64290	Chr7:3707306-3707333 (+)	285 bp
Tssr64291	Chr7:3707555-3707585 (+)	535 bp
Tssr64292	Chr7:3707677-3707690 (+)	649 bp
Tssr64293	Chr7:3708024-3708041 (+)	998 bp
Tssr64294	Chr7:3708714-3708738 (+)	1,691 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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