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Ppp1r11 Gene Detail
Summary
  • Symbol
    Ppp1r11
  • Name
    protein phosphatase 1, regulatory inhibitor subunit 11
  • Synonyms
    1500041B02Rik, HCG-V, HCGV, Tcte5, Tctex-5, Tctex5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923747
    NCBI Gene: 76497
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:37259248-37262633 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923747
 protein coding gene Chr17:37259247-37262684 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023688
 protein coding gene Chr17:37304339-37307723 (-)
A/J MGP_AJ_G0023646
 protein coding gene Chr17:36127628-36131012 (-)
AKR/J MGP_AKRJ_G0023617
 protein coding gene Chr17:36562481-36565863 (-)
BALB/cJ MGP_BALBcJ_G0023653
 protein coding gene Chr17:36370278-36373688 (-)
C3H/HeJ MGP_C3HHeJ_G0023415
 protein coding gene Chr17:37076528-37079903 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024091
 protein coding gene Chr17:38899040-38902425 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021559
 protein coding gene Chr17:33943049-33946350 (-)
CAST/EiJ MGP_CASTEiJ_G0022900
 protein coding gene Chr17:37208156-37211540 (-)
CBA/J MGP_CBAJ_G0023392
 protein coding gene Chr17:40417119-40420498 (-)
DBA/2J MGP_DBA2J_G0023517
 protein coding gene Chr17:35520279-35523664 (-)
FVB/NJ MGP_FVBNJ_G0023490
 protein coding gene Chr17:35128765-35132149 (-)
LP/J MGP_LPJ_G0023595
 protein coding gene Chr17:37834165-37837549 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023513
 protein coding gene Chr17:39211756-39215140 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024136
 protein coding gene Chr17:36902374-36905758 (-)
PWK/PhJ MGP_PWKPhJ_G0022652
 protein coding gene Chr17:34298808-34302188 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022471
 protein coding gene Chr17:34986882-34991568 (-)
WSB/EiJ MGP_WSBEiJ_G0022967
 protein coding gene Chr17:37221646-37225030 (-)



Homology
more
  • Human Ortholog
    PPP1R11, protein phosphatase 1 regulatory inhibitor subunit 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R11, protein phosphatase 1 regulatory inhibitor subunit 11
  • Synonyms
    CFAP255, HCG-V, HCGV, IPP3, TCTE5, TCTEX5
  • Links
    NCBI Gene ID: 6992
    neXtProt AC: NX_O60927
    UniProt: O60927

  • Chr Location
    6p22.1; chr6:30061265-30070333 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    53
  • cDNA Data
    122
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036398 Ensembl Gene Model | MGI Sequence Detail 3386 C57BL/6J ±  kb
transcript ENSMUST00000040402 Ensembl | MGI Sequence Detail 1599 Not Applicable  
polypeptide ENSMUSP00000047202 Ensembl | MGI Sequence Detail 131 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 134
    Genomic 10
    cDNA 122
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-14956, MGD-MRK-14970, MGI:2147023, MGI:98649
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:608 Ha H, et al., Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice. Dev Genet. 1991;12(4):318-32
  • Latest
    J:248448 McKelvey AC, et al., RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity. Elife. 2016 Nov 2;5:e18496
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory