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Saxo5 Gene Detail
Summary
  • Symbol
    Saxo5
  • Name
    stabilizer of axonemal microtubules 5
  • Synonyms
    1700019B03Rik, Tex45
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923656
    NCBI Gene: 76406
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:3520862-3537181 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 1.92 cM, cytoband A1.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    387 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923656
 protein coding gene Chr8:3515966-3537183 (+)
129S1/SvImJ ENSMUSG00200011347
 protein coding gene Chr8:335276-351371 (+)
A/J ENSMUSG00195009081
 protein coding gene Chr8:744349-760681 (+)
AKR/J ENSMUSG00220010647
 protein coding gene Chr8:470876-487210 (+)
BALB/cJ ENSMUSG00180004292
 protein coding gene Chr8:394941-411287 (+)
C3H/HeJ ENSMUSG00175007310
 protein coding gene Chr8:509464-525788 (+)
C57BL/6NJ ENSMUSG00215008411
 protein coding gene Chr8:423823-440149 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030769
 protein coding gene Chr8:337117-353495 (+)
CAST/EiJ ENSTCUG00005019477
 protein coding gene Chr8:485068-501205 (+)
CBA/J ENSMUSG00210010320
 protein coding gene Chr8:387036-403359 (+)
DBA/2J ENSMUSG00185003313
 protein coding gene Chr8:523080-539405 (+)
FVB/NJ ENSMUSG00205005450
 protein coding gene Chr8:456878-473206 (+)
JF1/MsJ ENSUMUG00000040219
 protein coding gene Chr8:471859-487955 (+)
LP/J ENSMUSG00230005666
 protein coding gene Chr8:2692659-2708984 (+)
NOD/ShiLtJ ENSMUSG00190010755
 protein coding gene Chr8:497099-513423 (+)
NZO/HlLtJ ENSMUSG00225016033
 protein coding gene Chr8:10559686-10576022 (+)
PWK/PhJ ENSLUMG00010010776
 protein coding gene Chr8:429117-445255 (+)
SPRET/EiJ ENSMSPG00010015681
 protein coding gene Chr8:402155-418642 (+)
WSB/EiJ ENSIUOG00005004262
 protein coding gene Chr8:433312-449602 (+)



Homology
more
  • Human Ortholog
    SAXO5, stabilizer of axonemal microtubules 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SAXO5, stabilizer of axonemal microtubules 5
  • Synonyms
    C19orf45, TEX45
  • Links
    NCBI Gene ID: 374877
    UniProt: Q8NA69

  • Chr Location
    19p13.2; chr19:7492976-7508450 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040340 Ensembl Gene Model | MGI Sequence Detail 16320 C57BL/6J ±  kb
transcript ENSMUST00000161680 Ensembl | MGI Sequence Detail 1526 Not Applicable  
polypeptide ENSMUSP00000124916 Ensembl | MGI Sequence Detail 500 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR028001 Stabilizer of axonemal microtubules 5
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:5882226, MGI:7482224
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory