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Txndc11 Gene Detail
Summary
  • Symbol
    Txndc11
  • Name
    thioredoxin domain containing 11
  • Synonyms
    2810408E11Rik, EF-hand binding protein 1, EFP1, Txdc11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923620
    NCBI Gene: 106200
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10892775-10952514 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 6.33 cM, cytoband B1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2342 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923620
 protein coding gene Chr16:10892775-10952541 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022520
 protein coding gene Chr16:7923237-7986006 (-)
A/J MGP_AJ_G0022482
 protein coding gene Chr16:7487162-7548050 (-)
AKR/J MGP_AKRJ_G0022458
 protein coding gene Chr16:7826453-7898144 (-)
BALB/cJ MGP_BALBcJ_G0022486
 protein coding gene Chr16:7621264-7688122 (-)
C3H/HeJ MGP_C3HHeJ_G0022253
 protein coding gene Chr16:7910864-7973545 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022935
 protein coding gene Chr16:8084373-8152254 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020455
 protein coding gene Chr16:7646461-7706140 (-)
CAST/EiJ MGP_CASTEiJ_G0021780
 protein coding gene Chr16:7934062-7997095 (-)
CBA/J MGP_CBAJ_G0022222
 protein coding gene Chr16:8441383-8501960 (-)
DBA/2J MGP_DBA2J_G0022353
 protein coding gene Chr16:7494424-7554551 (-)
FVB/NJ MGP_FVBNJ_G0022329
 protein coding gene Chr16:7485800-7546896 (-)
LP/J MGP_LPJ_G0022421
 protein coding gene Chr16:7876181-7942565 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022351
 protein coding gene Chr16:8128878-8194489 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022948
 protein coding gene Chr16:7775891-7845208 (-)
PWK/PhJ MGP_PWKPhJ_G0021520
 protein coding gene Chr16:7709519-7772692 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021350
 protein coding gene Chr16:7844157-7905106 (-)
WSB/EiJ MGP_WSBEiJ_G0021828
 protein coding gene Chr16:7869541-7931859 (-)



Homology
more
  • Human Ortholog
    TXNDC11, thioredoxin domain containing 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TXNDC11, thioredoxin domain containing 11
  • Synonyms
    EFP1
  • Links
    NCBI Gene ID: 51061
    UniProt: Q6PKC3

  • Chr Location
    16p13.13; chr16:11679083-11742857 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    59
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022498 Ensembl Gene Model | MGI Sequence Detail 59740 C57BL/6J ±  kb
    transcript ENSMUST00000038424 Ensembl | MGI Sequence Detail 3095 Not Applicable  
    polypeptide ENSMUSP00000041113 Ensembl | MGI Sequence Detail 948 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      9 Sequences
    • Protein Ontology
      PR:000016857 thioredoxin domain-containing protein 11
      (term hierarchy)
    • InterPro Domains
      IPR013766 Thioredoxin domain
      IPR052792 Thioredoxin domain-containing protein 11
      IPR036249 Thioredoxin-like superfamily
    • GlyGen
      Q8K2W3 5 sites, 2 N-linked glycans (4 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 59
      cDNA 59

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2146427
    References
    more
    • Summaries
      All 31
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory