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Pgcka1 Gene Detail
Summary
  • Symbol
    Pgcka1
  • Name
    PDCD10 and GCKIII kinases associated 1
  • Synonyms
    0610040J01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923511
    NCBI Gene: 76261
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:63969833-64056968 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 32.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2404 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923511
 protein coding gene Chr5:63969706-64056968 (+)
129S1/SvImJ ENSMUSG00200000039
 protein coding gene Chr5:59583031-59670295 (+)
A/J ENSMUSG00195000191
 protein coding gene Chr5:58942836-59023837 (+)
AKR/J ENSMUSG00220006899
 protein coding gene Chr5:59079627-59160608 (+)
BALB/cJ ENSMUSG00180005914
 protein coding gene Chr5:58733694-58814533 (+)
C3H/HeJ ENSMUSG00175001710
 protein coding gene Chr5:60774208-60855130 (+)
C57BL/6NJ ENSMUSG00215002712
 protein coding gene Chr5:59514561-59601824 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027234
 protein coding gene Chr5:57133971-57213727 (+)
CAST/EiJ ENSTCUG00005000351
 protein coding gene Chr5:58701191-58782597 (+)
CBA/J ENSMUSG00210000090
 protein coding gene Chr5:59670643-59751630 (+)
DBA/2J ENSMUSG00185005162
 protein coding gene Chr5:61544626-61625542 (+)
FVB/NJ ENSMUSG00205009700
 protein coding gene Chr5:58478825-58559800 (+)
JF1/MsJ ENSUMUG00000014757
 protein coding gene Chr5:66046473-66127457 (+)
LP/J ENSMUSG00230006842
 protein coding gene Chr5:66198586-66285850 (+)
NOD/ShiLtJ ENSMUSG00190000191
 protein coding gene Chr5:58666533-58747512 (+)
NZO/HlLtJ ENSMUSG00225008858
 protein coding gene Chr5:71320956-71401932 (+)
PWK/PhJ ENSLUMG00010004000
 protein coding gene Chr5:58653736-58734296 (+)
SPRET/EiJ ENSMSPG00010029891
 protein coding gene Chr5:60457843-60539429 (+)
WSB/EiJ ENSIUOG00005000053
 protein coding gene Chr5:61642002-61723284 (+)



Homology
more
  • Human Ortholog
    PGCKA1, PDCD10 and GCKIII kinases associated 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PGCKA1, PDCD10 and GCKIII kinases associated 1
  • Synonyms
    C4orf19
  • Links
    NCBI Gene ID: 55286
    UniProt: Q8IY42

  • Chr Location
    4p14; chr4:37453255-37624344 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    37
  • cDNA Data
    53
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76261 NCBI Gene Model | MGI Sequence Detail 87136 C57BL/6J ±  kb
    transcript NM_001417897 RefSeq | MGI Sequence Detail 2144 C57BL/6  
    polypeptide Q99K99 UniProt | EBI | MGI Sequence Detail 313 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000059917 PDCD10 and GCKIII kinases-associated protein 1
      (term hierarchy)
    • InterPro Domains
      IPR031528 PDCD10 and GCKIII kinases-associated protein 1 C4orf19/PGCKA1
    • GlyGen
      Q99K99 3 sites
    Molecular
    Reagents
    less
    • All nucleic 53
      cDNA 53

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2140955, MGI:7790832
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 4
      Gene Ontology 4
      Phenotypes 23
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory